ArticleFrontiers in medicine2024
The systemic immune-inflammation index is significantly associated with the severity of silicosis: a 9-year retrospective study in Beijing.
Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Association between systemic inflammation-immune index and comorbidities in patients with ankylosing spondylitis: a cross-sectional study.Clinical rheumatology · 2026Article
- Accessible Blood Based Biomarkers Reflecting Inflammation-Lipid Dysregulation in Silicosis Progression - Jiangsu Province, China, 2021-2024.China CDC weekly · 2026Article
- Long-term survival and the critical role of competing risks in pneumoconiosis: a large-scale retrospective cohort study.Frontiers in public health · 2026Article
- Diagnostic potential of serum ACE and CBC inflammatory markers in silicosis in the ceramic workers.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025Article
- Unveiling the threat of crystalline silica on the cardiovascular system. A comprehensive review of the current knowledge.Frontiers in cardiovascular medicine · 2025Review
- Development of a machine learning-based risk prediction model for early-stage pneumoconiosis: a retrospective study.Frontiers in medicine · 2025Article
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Abstract
Background: Silicosis shows an increasing trend with the development of new industries. However, the potential biomarkers for predicting the disease severity are lacking. A novel inflammatory marker, the systemic immune-inflammation Index (SII), has not been studied in silicosis. Methods: In this retrospective study, we used data from a big database platform of a tertiary general hospital in Beijing, which was established based on the electronic medical records of the hospital. The clinical data of adult patients diagnosed with silicosis at the Department of Occupational Medicine and Toxicology from 2013 to 2022 were collected. The data extracted from the database were in de-identified form. Only patients with a first diagnosis of silicosis and without conditions that might affect the parameters of routine blood tests were included in the analysis. Analyses were performed to assess the relationship between SII and the advanced stage of silicosis. Results: A total of 246 participants were included in the study. Most of the patients were exposed to silica particles during excavation and digging ( Conclusion: Higher SII is associated with the advanced stage of silicosis and impaired lung function. More long-term, large-scale studies are needed to confirm these findings.
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