Evidence map›Paper›PMID 38384301›Full record

ArticleFrontiers in cellular and infection microbiology2024

The role of type VI secretion system genes in antibiotic resistance and virulence in

Pu Li, Sirui Zhang, Jingdan Wang, Mona Mohamed Al-Shamiri, Kai Luo, Shuyan Liu, Peng Mi, Xiaokang Wu, Haiping Liu, Huohuan Tian and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Drug-resistantClinical microbiology reviews · 2025
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  13. Recent advances in host models in studying virulence factors and pathogenesis ofFrontiers in cellular and infection microbiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Pu LiSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Sirui ZhangDepartment of Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Jingdan WangSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Mona Mohamed Al-ShamiriDepartment of Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Kai LuoDepartment of Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Shuyan LiuDepartment of Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Peng MiDepartment of Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Xiaokang WuDepartment of Laboratory Medicine, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Haiping LiuDepartment of Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Huohuan TianDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Bei HanSchool of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Jin'e LeiDepartment of Laboratory Medicine, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Shaoshan HanDepartment of Hepatobiliary Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Lei HanDepartment of Microbiology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Xi'an Jiaotong University · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CNShanxi Medical University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The type VI secretion system (T6SS) is a crucial virulence factor in the nosocomial pathogen Methods: The importance of three representative T6SS core genes involved in the drug resistance and virulence of Results: A higher ratio of the three core genes was detected in drug-resistant strains than in susceptible strains among our 114 Discussion: The above results suggest that T6SS plays an important role, participating in the antibiotic resistance of

Indexed as

Acinetobacter baumanniiType VI Secretion SystemsAnti-Bacterial AgentsDrug Resistance, MicrobialHumansOfloxacinVirulenceAnti-Bacterial AgentsOfloxacinType VI Secretion SystemsAcinetobacter baumanniiantimicrobial resistanceT6SSTssBTssDTSSMvirulence

Identifiers

PMID38384301
PMCPMC10879597
OpenAlexW4391609610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.