Evidence map›Paper›PMID 38383788›Full record

ArticleNature2024

Synaptic wiring motifs in posterior parietal cortex support decision-making.

Aaron T Kuan, Giulio Bondanelli, Laura N Driscoll, Julie Han, Minsu Kim, David G C Hildebrand, Brett J Graham, Daniel E Wilson, Logan A Thomas, Stefano Panzeri and 2 more

Open access · greenAbstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
17.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 59 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Aaron T Kuan *Department of Neurobiology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-1908-7949
Giulio Bondanelli *Neural Computation Laboratory, Istituto Italiano di Tecnologia, Genoa, Italy.ORCID 0000-0001-6781-4939
Laura N DriscollDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
Julie HanDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
Minsu KimDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
David G C HildebrandDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-2079-3517
Brett J GrahamDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
Daniel E WilsonDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
Logan A ThomasDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.
Stefano PanzeriNeural Computation Laboratory, Istituto Italiano di Tecnologia, Genoa, Italy. s.panzeri@uke.de.ORCID 0000-0003-1700-8909
Christopher D HarveyDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA. christopher_harvey@hms.harvard.edu.
Wei-Chung Allen LeeDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA. wei-chung_lee@hms.harvard.edu.ORCID 0000-0002-4618-295X
Harvard University · USUniversität Hamburg · DEBoston Children's Hospital · USNortheastern University · USSpace Telescope Science Institute · US

Funding

Toward mechanistic cognitive neuroscience: cell types, connectivity, and patterned perturbationsDP1MH125776 · NIMH · HARVARD MEDICAL SCHOOL · PI HARVEY, CHRISTOPHER D · 2020 to 2024
$5.9M
Studying perceptual decision-making across cortex by combining population imaging, connectomics, and computational modelingR01NS108410 · NINDS · HARVARD MEDICAL SCHOOL · PI HARVEY, CHRISTOPHER D, LEE, WEI-CHUNG ALLEN · 2018 to 2022
$5.7M
Parietal Cortex Networks for Sensorimotor Processing During NavigationR01NS089521 · NINDS · HARVARD MEDICAL SCHOOL · PI HARVEY, CHRISTOPHER D · 2015 to 2024
$4.5M
Orchestra: A high performance biomedical supercomputing collaborativeS10RR028832 · NCRR · HARVARD MEDICAL SCHOOL · PI DANUSER, GAUDENZ · 2010 to 2010
$3.7M
Cerebellar network mapping with a high-throughput TEM platformRF1MH114047 · NIMH · HARVARD MEDICAL SCHOOL · PI LEE, WEI-CHUNG ALLEN · 2017 to 2017
$1.3M
Optical measurement of causal functional connectivity in posterior parietal cortexF32MH118698 · NIMH · HARVARD MEDICAL SCHOOL · PI WILSON, DANIEL E · 2018 to 2021
$204k
Brain-wide Neuronal Circuit Mapping with X-ray Nano-HolographyK99EB032217 · NIBIB · HARVARD MEDICAL SCHOOL · PI KUAN, AARON · 2021 to 2022
$180k
NCRR NIH HHS S10 RR028832NIBIB NIH HHS K99 EB032217NIMH NIH HHS DP1 MH125776NIMH NIH HHS F32 MH118698NIMH NIH HHS RF1 MH114047NINDS NIH HHS R01 NS089521NINDS NIH HHS R01 NS108410
6 · The paper itself

Abstract

The posterior parietal cortex exhibits choice-selective activity during perceptual decision-making tasks

Indexed as

Decision MakingNeural PathwaysParietal LobeSynapsesCalciumInterneuronsLearningMicroscopy, ElectronModels, NeurologicalNeural InhibitionPyramidal CellsVirtual RealityCalcium

Identifiers

PMID38383788
PMCPMC11162200
OpenAlexW4391994093

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.