ArticleNature2024
UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
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In one paragraph
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
13.8field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 49 citations in OpenAlex.
- Adjunctive nebulization of Idursulfase to intravenous treatment enhances cardiac proteome adaptations in IDS-KO mice.bioRxiv : the preprint server for biology · 2026Article
- Ubiquitin and ubiquitin-like modifications in the endoplasmic reticulum stress response.The FEBS journal · 2026Review
- Narrative review-the emerging role, functions, and mechanisms of UFMylation in cancers.Translational cancer research · 2026Review
- Mapping the architecture of protein complexes inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Evaluating evidence for UFMylation client diversity.Nature reviews. Molecular cell biology · 2026Article
- The mechanistic basis and cellular functions of UFMylation.Nature reviews. Molecular cell biology · 2026Review
- The coordinated action of UFMylation and the RQC pathways clears arrested polypeptides at the ER.The EMBO journal · 2026Article
- Survey of the human proteostasis network: the ubiquitin-proteasome system.bioRxiv : the preprint server for biology · 2026Article
- Encephalopathy-linked UFM1 variants impede neuronal protein translation, development, and function.EMBO molecular medicine · 2026Article
- UFMylation of Pyruvate Dehydrogenase Regulates Mitochondrial Metabolism.bioRxiv : the preprint server for biology · 2026Article
- Ribosome-associated quality control and related mechanisms.Nature structural & molecular biology · 2026Review
- The UFM1 Conjugation System: A Master Regulator of Cellular Stress Surveillance in Human Disease.Biology · 2026Review
- Signal recognition particle-dependent secretome in humans.Scientific reports · 2026Article
- Differential regulation of translational stress responses by herpesvirus ubiquitin deconjugases.The FEBS journal · 2026Article
- Quality control and signaling pathways at stalled ribosomes.Experimental & molecular medicine · 2026Review
- Targeting the UFL1-AKT cascade suppresses triple-negative breast cancer progression.Nature communications · 2026Article
- UFM1 regulates ferroptosis in oral squamous cell carcinoma by stabilizing SLC7A11.American journal of cancer research · 2026Article
- UFM1 at the endoplasmic reticulum: linking ER stress, ribosome quality control, and ER-phagy.Essays in biochemistry · 2025Review
- WBP11 inhibits UFL1-mediated UFMylation of NONO to drive hepatocellular carcinoma progression.Oncogene · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 6 institutions in 3 countries.
Paul A DaRosa *Department of Biology, Stanford University, Stanford, CA, USA.ORCID 0000-0001-7214-8758
Ivan Penchev *Department of Biochemistry, Gene Center, University of Munich, Munich, Germany.
Samantha C GumbinDepartment of Biology, Stanford University, Stanford, CA, USA.ORCID 0000-0002-0257-509X
Francesco ScavoneDepartment of Biology, Stanford University, Stanford, CA, USA.ORCID 0000-0003-3560-7120
Magda WąchalskaDepartment of Biology, Stanford University, Stanford, CA, USA.ORCID 0000-0003-0429-888X
Joao A PauloDepartment of Cell Biology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-4291-413X
Alban OrdureauDepartment of Cell Biology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-4924-8520
Joshua J PeterMedical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU), School of Life Sciences, University of Dundee, Dundee, UK.
Yogesh KulathuMedical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU), School of Life Sciences, University of Dundee, Dundee, UK.ORCID 0000-0002-3274-1642
J Wade HarperDepartment of Cell Biology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-6944-7236
Thomas BeckerDepartment of Biochemistry, Gene Center, University of Munich, Munich, Germany.ORCID 0000-0001-8458-2738
Roland BeckmannDepartment of Biochemistry, Gene Center, University of Munich, Munich, Germany. beckmann@genzentrum.lmu.de.ORCID 0000-0003-4291-3898
Ron R KopitoDepartment of Biology, Stanford University, Stanford, CA, USA. kopito@stanford.edu.ORCID 0000-0001-5027-6935
Stanford University · USHarvard University · USUniversity of Dundee · GBGene Therapy Laboratory · FRMemorial Sloan Kettering Cancer Center · USStanford Medicine · US
Funding
The Stanford-SLAC CryoEM Center supplementU24GM129541 · NIGMS · STANFORD UNIVERSITY · PI CHIU, WAH, HEDMAN, BRITT · 2018 to 2023
$54.8MSupplement to Enhance Wellness and Resiliency in the Graduate EnvironmentT32GM007276 · NIGMS · STANFORD UNIVERSITY · PI MORRISON, ASHBY J. · 1985 to 2023
$32.9MUbiquitin Mediated Proteolysis and Cell Cycle ControlR01AG011085 · NIA · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI JEFFREY W HARPER · 1993 to 2026
$10.9MThe Ubiquitin Proteasome System in Quality ControlR01GM074874 · NIGMS · STANFORD UNIVERSITY · PI KOPITO, RON R · 2006 to 2022
$8.0MEPILEPSY TRAINING PROGRAMT32NS007280 · NINDS · STANFORD UNIVERSITY · PI HUGUENARD, JOHN R · 1985 to 2020
$3.6MThe role of UFMylation in ribosome quality control at the ERR01GM148477 · NIGMS · STANFORD UNIVERSITY · PI RON R KOPITO · 2023 to 2026
$2.4MRegulation of PINK1 and PARKIN-Dependent MitophagyR01NS083524 · NINDS · HARVARD MEDICAL SCHOOL · PI HARPER, JEFFREY W · 2020 to 2024
$2.2MResolving the role of nicotine-mediated phosphorylation on pancreatic fibrosisK01DK098285 · NIDDK · HARVARD MEDICAL SCHOOL · PI PAULO, JOAO A · 2013 to 2017
$638kNIA NIH HHS R01 AG011085NIDDK NIH HHS K01 DK098285NIGMS NIH HHS R01 GM074874NIGMS NIH HHS R01 GM148477NIGMS NIH HHS T32 GM007276NIGMS NIH HHS U24 GM129541NINDS NIH HHS R01 NS083524NINDS NIH HHS T32 NS007280
Abstract
Reversible modification of target proteins by ubiquitin and ubiquitin-like proteins (UBLs) is widely used by eukaryotic cells to control protein fate and cell behaviour
Indexed as
Endoplasmic ReticulumProtein Processing, Post-TranslationalRibosome Subunits, Large, EukaryoticUbiquitin-Protein LigasesBinding SitesBiocatalysisCryoelectron MicroscopyIntracellular MembranesPeptidyl TransferasesProtein BindingRibosomal ProteinsRNA, TransferSubstrate SpecificityPeptidyl TransferasesRibosomal ProteinsRNA, TransferUbiquitin-Protein Ligases
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.