Evidence map›Paper›PMID 38383746›Full record

ArticleNature methods2024

A-SOiD, an active-learning platform for expert-guided, data-efficient discovery of behavior.

Jens F Tillmann, Alexander I Hsu, Martin K Schwarz, Eric A Yttri

Abstract read
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In one paragraph

Article in Nature methods, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. ABEL: an active-learning behavior estimation and labeling platform.bioRxiv : the preprint server for biology · 2026
    Article
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  7. Optogenetic Analysis of Behavior in the MosquitobioRxiv : the preprint server for biology · 2026
    Article
  8. Neural Bases of Collective Social Behavior and Group Interactions across Species.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jens F Tillmann *Institute of Experimental Epileptology and Cognition Research, University of Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0002-3030-1571
Alexander I Hsu *Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0002-8198-945X
Martin K SchwarzInstitute of Experimental Epileptology and Cognition Research, University of Bonn, Bonn, Germany. Martin.Schwarz@ukbonn.de.ORCID http://orcid.org/0000-0002-5898-751X
Eric A YttriDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, USA. eyttri@andrew.cmu.edu.ORCID http://orcid.org/0000-0002-7214-1481

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To identify and extract naturalistic behavior, two methods have become popular: supervised and unsupervised. Each approach carries its own strengths and weaknesses (for example, user bias, training cost, complexity and action discovery), which the user must consider in their decision. Here, an active-learning platform, A-SOiD, blends these strengths, and in doing so, overcomes several of their inherent drawbacks. A-SOiD iteratively learns user-defined groups with a fraction of the usual training data, while attaining expansive classification through directed unsupervised classification. In socially interacting mice, A-SOiD outperformed standard methods despite requiring 85% less training data. Additionally, it isolated ethologically distinct mouse interactions via unsupervised classification. We observed similar performance and efficiency using nonhuman primate and human three-dimensional pose data. In both cases, the transparency in A-SOiD's cluster definitions revealed the defining features of the supervised classification through a game-theoretic approach. To facilitate use, A-SOiD comes as an intuitive, open-source interface for efficient segmentation of user-defined behaviors and discovered sub-actions.

Indexed as

LearningProblem-Based LearningAnimalsHumansMice

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.