Evidence map›Paper›PMID 38383740›Full record

ArticleCommunications medicine2024

Phenotypic and genomic characteristics of clinical IMP-producing Klebsiella spp. Isolates in China.

Congcong Liu, Ning Dong, Yanyan Zhang, Qiaoling Sun, Yonglu Huang, Chang Cai, Gongxiang Chen, Rong Zhang

Open access · goldAbstract read
In one paragraph

Article in Communications medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 citations in OpenAlex.

  1. Genomic characterization ofMicrobiology spectrum · 2026
    Article
  2. Role of Mobilome in Carbapenem Resistance.Antibiotics (Basel, Switzerland) · 2026
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  3. Coexistence ofFrontiers in microbiology · 2026
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  4. Article
  5. Encoding Genes of Metallo β-Lactamases (Health science reports · 2025
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Congcong LiuDepartment of Clinical Laboratory, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China.ORCID http://orcid.org/0000-0002-1989-6711
Ning DongDepartment of Medical Microbiology, School of Biology and Basic Medical Science, Medical College of Soochow University, Suzhou, Jiangsu, China.
Yanyan ZhangDepartment of Clinical Laboratory, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China.
Qiaoling SunDepartment of Clinical Laboratory, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China.
Yonglu HuangDepartment of Clinical Laboratory, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China.
Chang CaiCollege of Animal Science and Technology, College of Veterinary Medicine, Zhejiang Agriculture and Forestry University, Hangzhou, China.
Gongxiang ChenDepartment of Clinical Laboratory, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China. chengongxiang@zju.edu.cn.
Rong ZhangDepartment of Clinical Laboratory, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China. zhang-rong@zju.edu.cn.ORCID http://orcid.org/0000-0002-2174-7985
Second Affiliated Hospital of Zhejiang University · CNSoochow University · CNZhejiang A & F University · CN

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82072341National Natural Science Foundation of China (National Science Foundation of China) 82272392
6 · The paper itself

Abstract

backgroundIMP-producing Klebsiella spp. (IMPKsp) strains have spread globally, including in China. Currently, the prevalence and genomic characterization of IMPKsp is largely unknown nationwide. Here we aimed to provide a general overview of the phenotypic and genomic characteristics of IMPKsp strains.

methods61 IMPKsp strains were obtained from 13 provinces in China during 2016-2021. All strains were tested for their susceptibility to antimicrobial agents by the microdilution broth method and sequenced with Illumina next-generation sequencing. We performed conjugation experiments on thirteen representative strains which were also sequenced by Oxford nanopore sequencing technology to characterize bla

resultsWe find that all IMPKsp strains display multidrug-resistant (MDR) phenotypes. All strains belong to 27 different STs. ST307 emerges as a principal IMP-producing sublineage. bla

conclusionsOur results highlight that multi-clonal transmission, multiple genetic environments and plasmid types play a major role in the dissemination process of bla

Identifiers

PMID38383740
PMCPMC10881498
OpenAlexW4392000743

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.