Evidence map›Paper›PMID 38383739›Full record

ArticleScientific reports2024

Dynamic hydrogen peroxide levels reveal a rate-dependent sensitivity in B-cell lymphoma signaling.

Melde Witmond, Emma Keizer, Bas Kiffen, Wilhelm T S Huck, Jessie A G L van Buggenum

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Melde WitmondInstitute for Molecules and Materials (IMM), Radboud University Nijmegen, Nijmegen, The Netherlands.
Emma KeizerInstitute for Molecules and Materials (IMM), Radboud University Nijmegen, Nijmegen, The Netherlands.
Bas KiffenInstitute for Molecules and Materials (IMM), Radboud University Nijmegen, Nijmegen, The Netherlands.
Wilhelm T S HuckInstitute for Molecules and Materials (IMM), Radboud University Nijmegen, Nijmegen, The Netherlands. wilhelm.huck@ru.nl.
Jessie A G L van BuggenumInstitute for Molecules and Materials (IMM), Radboud University Nijmegen, Nijmegen, The Netherlands. jessie.vanbuggenum@ru.nl.
Radboud University Nijmegen · NL

Funding

Nederlandse Organisatie voor Wetenschappelijk Onderzoek SpinozaNederlandse Organisatie voor Wetenschappelijk Onderzoek VENI 202.228
6 · The paper itself

Abstract

Although in vivo extracellular microenvironments are dynamic, most in vitro studies are conducted under static conditions. Here, we exposed diffuse large B-cell lymphoma (DLBCL) cells to gradient increases in the concentration of hydrogen peroxide (H

Indexed as

Hydrogen PeroxideLymphoma, Large B-Cell, DiffuseHumansPhosphorylationReceptors, Antigen, B-CellSignal TransductionTumor MicroenvironmentHydrogen PeroxideReceptors, Antigen, B-Cell

Identifiers

PMID38383739
PMCPMC10882005
OpenAlexW4392001908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.