Evidence map›Paper›PMID 38383715›Full record

ArticleBone marrow transplantation2024

Prognostic factors in 448 newly diagnosed multiple myeloma receiving bortezomib-based induction: impact of ASCT, transplant refusal and high-risk MM.

Hoi Ki Karen Tang, Chi Yeung Fung, Yu Yan Hwang, Harold Lee, Grace Lau, Sze Fai Yip, Bonnie Kho, Chi Kuen Lau, Kwan Hung Leung, Elaine Au and 4 more

Abstract read
In one paragraph

Article in Bone marrow transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hoi Ki Karen TangDepartment of Medicine, Queen Mary Hospital, University of Hong Kong, Pok Fu Lam, Hong Kong.
Chi Yeung FungDepartment of Medicine, Queen Mary Hospital, University of Hong Kong, Pok Fu Lam, Hong Kong.
Yu Yan HwangDepartment of Medicine, Queen Mary Hospital, University of Hong Kong, Pok Fu Lam, Hong Kong.
Harold LeeDepartment of Medicine, Princess Margaret Hospital, Kwai Chung, Hong Kong.
Grace LauDepartment of Medicine, Princess Margaret Hospital, Kwai Chung, Hong Kong.
Sze Fai YipDepartment of Medicine, Tuen Mun Hospital, Tuen Mun, Hong Kong.
Bonnie KhoDepartment of Medicine, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong.
Chi Kuen LauDepartment of Medicine, Tseung Kwan O Hospital, Tseung Kwan O, Hong Kong.
Kwan Hung LeungDepartment of Medicine, United Christian Hospital, Kwun Tong, Hong Kong.
Elaine AuDepartment of Pathology, Queen Mary Hospital, University of Hong Kong, Pok Fu Lam, Hong Kong.
Eric TseDepartment of Medicine, Queen Mary Hospital, University of Hong Kong, Pok Fu Lam, Hong Kong.
Joycelyn SimDepartment of Medicine, Queen Mary Hospital, University of Hong Kong, Pok Fu Lam, Hong Kong.
Yok Lam KwongDepartment of Medicine, Queen Mary Hospital, University of Hong Kong, Pok Fu Lam, Hong Kong.ORCID 0000-0001-8156-6978
Chor Sang ChimDepartment of Medicine, Queen Mary Hospital, University of Hong Kong, Pok Fu Lam, Hong Kong. jcschim@hku.hk.ORCID 0000-0003-2427-915X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Hong Kong, newly diagnosed multiple myeloma (NDMM) receives bortezomib-based triplet induction. Upfront autologous stem cell transplant (ASCT) is offered to transplant eligible (TE) patients (NDMM ≤ 65 years of age), unless medically unfit (TE-unfit) or refused (TE-refused). Data was retrieved for 448 patients to assess outcomes. For the entire cohort, multivariate analysis showed that male gender (p = 0.006), international staging system (ISS) 3 (p = 0.003), high lactate dehydrogenase (LDH) (p = 7.6 × 10

Indexed as

BortezomibMultiple MyelomaTransplantation, AutologousAdultAgedFemaleHematopoietic Stem Cell TransplantationHumansMaleMiddle AgedPrognosisBortezomib

Identifiers

PMID38383715
PMCPMC11073964

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.