Evidence map›Paper›PMID 38383704›Full record

ArticleBritish journal of cancer2024

CAnceR IN PreGnancy (CARING) - a retrospective study of cancer diagnosed during pregnancy in the United Kingdom.

M A Baxter, M Denholm, S J Kingdon, S Kathirgamakarthigeyan, S Parikh, R Shakir, R Johnson, H Martin, M Walton, W Yao and 24 more

Abstract read
In one paragraph

Article in British journal of cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Cancer in pregnancy: FIGO Best practice advice and narrative review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Review
  4. Article
  5. Gastric cancer in pregnancy: a review.Future oncology (London, England) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

M A BaxterDivision of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK. m.z.baxter@dundee.ac.uk.ORCID 0000-0002-5773-8650
M DenholmDepartment of Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
S J KingdonExeter Oncology Centre, Royal Devon University Hospitals NHS Trust, Exeter, UK.
S KathirgamakarthigeyanOncology Department, Nottingham University Hospitals NHS Trust, Nottingham, UK.
S ParikhDepartment of Oncology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
R ShakirOncology Department, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
R JohnsonOncology Department, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
H MartinDepartment of Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
M WaltonDepartment of Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
W YaoDepartment of Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
A SwanEdinburgh Cancer Centre, Western General Hospital, NHS Lothian, Edinburgh, UK.
C SamuelsonEdinburgh Cancer Centre, Western General Hospital, NHS Lothian, Edinburgh, UK.
X RenEdinburgh Cancer Centre, Western General Hospital, NHS Lothian, Edinburgh, UK.
A CooperEdinburgh Cancer Centre, Western General Hospital, NHS Lothian, Edinburgh, UK.
H-L GrayTayside Cancer Centre, Ninewells Hospital and Medical School, NHS Tayside, Dundee, UK.
S CliftonBristol Haematology and Oncology Centre, Bristol, UK.
J BallBristol Haematology and Oncology Centre, Bristol, UK.
G GullickOncology Department, Royal United Hospitals NHS Foundation Trust, Bath, UK.
M AndersonNorthern Centre for Cancer Care, The Newcastle Upon Tyne Hospitals NHS Foundation Trust, The Newcastle Upon Tyne, UK.
L DoddNorthern Centre for Cancer Care, The Newcastle Upon Tyne Hospitals NHS Foundation Trust, The Newcastle Upon Tyne, UK.
H HayhurstNorthern Centre for Cancer Care, The Newcastle Upon Tyne Hospitals NHS Foundation Trust, The Newcastle Upon Tyne, UK.
M SalamaDepartment of Oncology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
R ShottonDepartment of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
F BrittonDepartment of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
T ChristodoulouDepartment of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
A Abdul-HamidDepartment of Oncology, Royal Surrey County Hospital NHS Trust, Surrey, UK.
A EichholzDepartment of Oncology, Buckinghamshire Healthcare NHS Trust, Buckinghamshire, UK.
R M EvansSouth West Wales Cancer Centre, Swansea Bay NHS Trust, Swansea, UK.
P WallrothMummy's Star, Glossop, UK.
F GibsonSchool of Health Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
K PooleThe Institute of Cancer Research, Clinical Trials and Statistics Unit, Belmont, Sutton, Surrey, UK.
M RoweSunrise Oncology Centre, Royal Cornwall Hospitals NHS Trust, Truro, UK.ORCID 0000-0001-8993-0148
J HarrisSchool of Health Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
National Oncology Trainees Collaborative for Healthcare Research (NOTCH)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of cancer diagnosed during pregnancy is increasing. Data relating to investigation and management, as well as maternal and foetal outcomes is lacking in a United Kingdom (UK) population.

methodsIn this retrospective study we report data from 119 patients diagnosed with cancer during pregnancy from 14 cancer centres in the UK across a five-year period (2016-2020).

resultsMedian age at diagnosis was 33 years, with breast, skin and haematological the most common primary sites. The majority of cases were new diagnoses (109 patients, 91.6%). Most patients were treated with radical intent (96 patients, 80.7%), however, gastrointestinal cancers were associated with a high rate of palliative intent treatment (63.6%). Intervention was commenced during pregnancy in 68 (57.1%) patients; 44 (37%) had surgery and 31 (26.1%) received chemotherapy. Live births occurred in 98 (81.7%) of the cases, with 54 (55.1%) of these delivered by caesarean section. Maternal mortality during the study period was 20.2%.

conclusionsThis is the first pan-tumour report of diagnosis, management and outcomes of cancer diagnosed during pregnancy in the UK. Our findings demonstrate proof of concept that data collection is feasible and highlight the need for further research in this cohort of patients.

Indexed as

Cesarean SectionNeoplasmsFemaleHumansLive BirthPregnancyRetrospective StudiesUnited Kingdom

Identifiers

PMID38383704
PMCPMC11014900

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.