ArticleFluids and barriers of the CNS2024
Pro-inflammatory cerebrospinal fluid profile of neonates with intraventricular hemorrhage: clinical relevance and contrast with CNS infection.
Article in Fluids and barriers of the CNS, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed, 5 citations in OpenAlex.
- Choroid plexus remodeling associated with inflammatory CSF exposure in preterm acquired hydrocephalus.iScience · 2026Article
- Clinical features, risk factors and outcomes of hydrocephalus in neonatal bacterial meningitis: a retrospective case-control study.Scientific reports · 2026Article
- Post-hemorrhagic hydrocephalus of prematurity is associated with disruption of tight junctions and increased macrophage activity in the choroid plexus.Fluids and barriers of the CNS · 2026Article
- Neutrophil-to-lymphocyte ratio and the risk of cerebrospinal fluid diversion after posterior fossa tumor resection in pediatrics.Neurosurgical review · 2026Article
- Safety and feasibility of dual external ventricular and lumbar drainage with rt-PA in intraventricular hemorrhage: A pilot study.Neurosurgical review · 2026Article
- Research priorities for non-invasive therapies to improve hydrocephalus outcomes.Fluids and barriers of the CNS · 2025Review
- Neuroinflammatory pathways and potential therapeutic targets in neonatal post-hemorrhagic hydrocephalus.Pediatric research · 2025Review
Corrections and comments
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Authors and funding
13 authors at 7 institutions in 1 country.
Funding
Abstract
backgroundInterpretation of cerebrospinal fluid (CSF) studies can be challenging in preterm infants. We hypothesized that intraventricular hemorrhage (IVH), post-hemorrhagic hydrocephalus (PHH), and infection (meningitis) promote pro-inflammatory CSF conditions reflected in CSF parameters.
methodsBiochemical and cytological profiles of lumbar CSF and peripheral blood samples were analyzed for 81 control, 29 IVH grade 1/2 (IVH
resultsPHH infants had higher (p < 0.02) CSF total cell and red blood cell (RBC) counts compared to control, IVH
conclusionsSimilarities in CSF parameters may reflect common pathological processes in the inflammatory response and show the complexity associated with interpreting CSF profiles, especially in PHH and meningitis/ventriculitis.
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What OpenQuestion holds
Registered trials
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