Evidence map›Paper›PMID 38383308›Full record

SynthesisExpert review of pharmacoeconomics & outcomes research2024

Using natural language processing to analyze unstructured patient-reported outcomes data derived from electronic health records for cancer populations: a systematic review.

Jin-Ah Sim, Xiaolei Huang, Madeline R Horan, Justin N Baker, I-Chan Huang

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Expert review of pharmacoeconomics & outcomes research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Jin-Ah SimDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, USA.
Xiaolei HuangDepartment of Computer Science, University of Memphis, Memphis, TN, USA.
Madeline R HoranDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, USA.
Justin N BakerDepartment of Pediatrics, Stanford University, Stanford, CA, USA.
I-Chan HuangDepartment of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, USA.
St. Jude Children's Research Hospital · USHallym University · KRUniversity of Memphis · US

Funding

Patient-Reported Outcomes Version of CTCAE involving Childhood Cancer SurvivorsR01CA238368 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI BAKER, JUSTIN N, HUANG, I-CHAN · 2019 to 2023
$3.5M
Training in Pediatric Cancer Survivorship Outcomes and InterventionsT32CA225590 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Kevin R Krull · 2018 to 2026
$2.4M
NCI NIH HHS R01 CA238368NCI NIH HHS T32 CA225590
6 · The paper itself

Abstract

introductionPatient-reported outcomes (PROs; symptoms, functional status, quality-of-life) expressed in the 'free-text' or 'unstructured' format within clinical notes from electronic health records (EHRs) offer valuable insights beyond biological and clinical data for medical decision-making. However, a comprehensive assessment of utilizing natural language processing (NLP) coupled with machine learning (ML) methods to analyze unstructured PROs and their clinical implementation for individuals affected by cancer remains lacking. AREAS COVERED: This study aimed to systematically review published studies that used NLP techniques to extract and analyze PROs in clinical narratives from EHRs for cancer populations. We examined the types of NLP (with and without ML) techniques and platforms for data processing, analysis, and clinical applications. EXPERT OPINION: Utilizing NLP methods offers a valuable approach for processing and analyzing unstructured PROs among cancer patients and survivors. These techniques encompass a broad range of applications, such as extracting or recognizing PROs, categorizing, characterizing, or grouping PROs, predicting or stratifying risk for unfavorable clinical results, and evaluating connections between PROs and adverse clinical outcomes. The employment of NLP techniques is advantageous in converting substantial volumes of unstructured PRO data within EHRs into practical clinical utilities for individuals with cancer.

Indexed as

Electronic Health RecordsMachine LearningNatural Language ProcessingNeoplasmsPatient Reported Outcome MeasuresQuality of LifeClinical Decision-MakingHumansCancerElectronic health recordsmachine learningnatural language processingPatient-reported outcomes

Identifiers

PMID38383308
PMCPMC11001514
OpenAlexW4392056731

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.