Evidence map›Paper›PMID 38383304›Full record

ArticleBMC anesthesiology2024

Operator gender differences in major mechanical complications after central line insertions: a subgroup analysis of a prospective multicentre cohort study.

Leila Naddi, Janna Hübinette, Thomas Kander, Ola Borgquist, Maria Adrian

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC anesthesiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03782324 (Mechanical Complications After Central Venous Catheterisation), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03782324 completednot on this map

Mechanical Complications After Central Venous Catheterisation

TypeobservationalSponsorRegion SkaneRan2019 to 2020Enrolled12,600ConditionsMechanical Complications of Central Venous Catheter
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Leila NaddiAnaesthesiology and Intensive Care, Department of Clinical Sciences, Lund University, Lund, Sweden. leila.naddi@med.lu.se.
Janna HübinetteMedical Faculty, Lund University, Lund, Sweden.
Thomas KanderAnaesthesiology and Intensive Care, Department of Clinical Sciences, Lund University, Lund, Sweden.
Ola BorgquistAnaesthesiology and Intensive Care, Department of Clinical Sciences, Lund University, Lund, Sweden.
Maria AdrianAnaesthesiology and Intensive Care, Department of Clinical Sciences, Lund University, Lund, Sweden.
Lund University · SESkåne University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA previous study on mechanical complications after central venous catheterisation demonstrated differences in complication rates between male and female operators. The objective of this subgroup analysis was to further investigate these differences. The hypothesis was that differences in distribution of predefined variables between operator genders could be identified.

methodsThis was a subgroup analysis of a prospective, multicentre, observational cohort study conducted between March 2019 and December 2020 including 8 586 patients ≥ 16 years receiving central venous catheters at four emergency care hospitals. The main outcome measure was major mechanical complications defined as major bleeding, severe cardiac arrhythmia, pneumothorax, arterial catheterisation, and persistent nerve injury. Independent t-test and χ

resultsFemale operators had a lower rate of major mechanical complications than male operators (0.4% vs 0.8%, P = .02), were less experienced (P < .001), had more patients with invasive positive pressure ventilation (P < .001), more often chose the internal jugular vein (P < .001) and more frequently used ultrasound guidance (P < .001). Male operators more often chose the subclavian vein (P < .001) and inserted more catheters with bore size ≥ 9 Fr (P < .001). Multivariable logistic regression analysis showed that male operator gender was associated with major mechanical complication (OR 2.67 [95% CI: 1.26-5.64]) after correction for other relevant independent variables.

conclusionsThe hypothesis was confirmed as differences in distribution of predefined variables between operator genders were found. Despite being less experienced, female operators had a lower rate of major mechanical complications. Furthermore, male operator gender was independently associated with a higher risk of major mechanical complications. Future studies are needed to further investigate differences in risk behaviour between male and female operators.

trial registrationClinicaltrials.gov identifier: NCT03782324. Date of registration: 20/12/2018.

Indexed as

Catheterization, Central VenousCentral Venous CathetersAdolescentAdultFemaleHumansJugular VeinsMaleMulticenter Studies as TopicObservational Studies as TopicProspective StudiesSex FactorsUltrasonographyCatheterisation, central venousCentral venous cathetersFemaleMaleMechanical complication

Identifiers

PMID38383304
PMCPMC10880374
OpenAlexW4392016837

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.