Evidence map›Paper›PMID 38383066›Full record

ArticleBrain and behavior2024

Correlation of GABA

Yinghui Duan, Qianyun Rui, Yang Yang, Jingluan Tian, Shugang Cao, Feng Zhu, Xiaoyu Duan, Hanqing Gao, Xiaopei Ji, Xinyi Xiao and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. The association between information processing speed and clinical features in people with multiple sclerosis and neuromyelitis optica: a comparative study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  2. Correlation of GABABrain and behavior · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yinghui Duan *Department of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0001-6110-8160
Qianyun Rui *Department of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yang Yang *Department of Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Jingluan TianDepartment of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Shugang CaoDepartment of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Feng ZhuDepartment of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Xiaoyu DuanDepartment of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Hanqing GaoDepartment of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Xiaopei JiDepartment of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Xinyi XiaoDepartment of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yonggang LiDepartment of Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Qun XueDepartment of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Soochow University · CNAnhui Medical University · CN

Funding

Jiangsu Provincial Key Research and Development Program (Social Development) Clinical Frontier Technology Key Project BE2019666Natural Science Foundation of Jiangsu Province BK20211075The Collaborative Innovation Center of Soochow University (Horizontal Scientific Research Project) H230028
6 · The paper itself

Abstract

backgroundNeuromyelitis optica spectrum disorder (NMOSD) associated with cognitive impairment (CI) is acknowledged. However, the underlying pathogenesis and involvement of the immune system remain unclear.

objectivesThis study aimed to investigate the alterations in immune cells, cytokines, and GABA

methodsThirty-eight NMOSD patients and 38 healthy controls (HCs) were included. NMOSD patients were stratified as NMOSD-CI and NMOSD-CP groups. The difference in cognitive functions, Tfh and cytokines, and GABA

resultsNMOSD-CI patients showed worse performance on all cognitive tests, and the percentage of circulating follicular helper T cells (cTfh) was significantly elevated. The frequency of cTfh was positively and negatively correlated with Stroop-A and AVLT long-delayed scores, respectively. IL-21 was remarkably higher in NMOSD-CI and NMOSD-CP. The level of GABA

conclusionIn NMOSD-CI patients, all cognitive domains were impacted, , while GABA

Indexed as

Cognitive DysfunctionNeuromyelitis OpticaCytokinesgamma-Aminobutyric AcidHumansPrefrontal CortexT Follicular Helper CellsCytokinesgamma-Aminobutyric Acidcognitive impairmentfollicular helper T cellsGABAneuromyelitis optica

Identifiers

PMID38383066
PMCPMC10881283
OpenAlexW4392316534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.