Evidence map›Paper›PMID 38383038›Full record

ArticleBMJ (Clinical research ed.)2024

Optimal timing of influenza vaccination in young children: population based cohort study.

Christopher M Worsham, Charles F Bray, Anupam B Jena

Open access · hybridAbstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Christopher M WorshamDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Charles F BrayDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Anupam B JenaDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA jena@hcp.med.harvard.edu.ORCID 0000-0002-9734-5122
Harvard University · USNational Bureau of Economic Research · US

Funding

Use of Inter-Hospital Transfer Services in Critical Illness and Acute Respiratory FailureK08HS029197 · AHRQ · MASSACHUSETTS GENERAL HOSPITAL · PI WORSHAM, CHRISTOPHER MOORE · 2023 to 2025
$468k
AHRQ HHS K08 HS029197
6 · The paper itself

Abstract

objectiveTo assess optimal timing of influenza vaccination in young children.

designPopulation based cohort study.

settingUnited States.

participantsCommercially insured children aged 2-5 years who were vaccinated against influenza during 2011-18.

main outcome measureRates of diagnosis of influenza among children who were vaccinated against influenza, by birth month.

resultsOverall, 819 223 children aged 2-5 received influenza vaccination. Children vaccinated in November and December were least likely to have a diagnosis of influenza, a finding that may be confounded by unmeasured factors that influence the timing of vaccination and risk of influenza. Vaccination commonly occurred on days of preventive care visits and during birth months. Children born in October were disproportionately vaccinated in October and were, on average, vaccinated later than children born in August and earlier than those born in December. Children born in October had the lowest rate of influenza diagnosis (for example, 2.7% (6016/224 540) versus 3.0% (6462/212 622) for those born in August; adjusted odds ratio 0.88, 95% confidence interval 0.85 to 0.92).

conclusionsIn a quasi-experimental analysis of young children vaccinated against influenza, birth month was associated with the timing of vaccination through its influence on the timing of preventive care visits. Children born in October were most likely to be vaccinated in October and least likely to have a diagnosis of influenza, consistent with recommendations promoting October vaccination.

Indexed as

Influenza, HumanInfluenza VaccinesChildChild, PreschoolCohort StudiesFemaleHumansOdds RatioParturitionPregnancyUnited StatesVaccinationInfluenza Vaccines

Identifiers

PMID38383038
PMCPMC10879981
OpenAlexW4392057457

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.