Evidence map›Paper›PMID 38381886›Full record

ArticleJournal of medicinal chemistry2024

Discovery of 5-Hydroxy-1,4-naphthoquinone (Juglone) Derivatives as Dual Effective Agents Targeting Platelet-Cancer Interplay through Protein Disulfide Isomerase Inhibition.

Yu-Pu Juang, Ju-Ying Tsai, Wan-Lan Gu, Hui-Ching Hsu, Chao-Lung Lin, Chin-Chung Wu, Pi-Hui Liang

Open access · hybridAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  3. Current issues in molecular biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yu-Pu JuangSchool of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Ju-Ying TsaiGraduate Institute of Natural Product, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Wan-Lan GuSchool of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Hui-Ching HsuGraduate Institute of Natural Product, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Chao-Lung LinSchool of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Chin-Chung WuGraduate Institute of Natural Product, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Pi-Hui LiangSchool of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan.ORCID 0000-0001-6668-4642
National Taiwan University · TWKaohsiung Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, a series of 2- and/or 3-substituted juglone derivatives were designed and synthesized. Among them,

Indexed as

Antineoplastic AgentsNaphthoquinonesNeoplasmsBlood PlateletsHumansMolecular Docking SimulationProtein Disulfide-IsomerasesAntineoplastic AgentsjugloneNaphthoquinonesProtein Disulfide-Isomerases

Identifiers

PMID38381886
PMCPMC10945480
OpenAlexW4392015793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.