ArticleCadernos de saude publica2024
Post-COVID-19 syndrome: persistent symptoms, functional impact, quality of life, return to work, and indirect costs - a prospective case study 12 months after COVID-19 infection.
Article in Cadernos de saude publica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Factors influencing work ability and return-to-work in individuals affected by post-COVID: a systematic review.BMC public health · 2026Pooled it
- Systematic Review of Dyspnea and Chronic Fatigue in Patients With Long COVID: Clinical Characteristics and Associated Laboratory Parameters.Pulmonary medicine · 2026Pooled it
- Effects of inspiratory muscle training on exercise capacity, muscle oxygenation and strength, physical activity, and dyspnea in patients with post-COVID-19 syndrome and pulmonary involvement: a randomized controlled triple-blinded study.BMC pulmonary medicine · 2026Trial
- Recovery-phase symptoms after COVID-19 infection and anxiety levels among college students.Frontiers in psychiatry · 2026Article
- Quality of life of people with and without respiratory complications in post-COVID-19 syndrome: a retrospective study.Revista brasileira de enfermagem · 2026Observational
- Factors associated with post-COVID-19 health conditions at a rehabilitation center: a cross-sectional study, Paraíba, Brazil, 2024.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2026Article
- Post-COVID-19 social determinants of health and quality of life: a longitudinal study.Revista da Escola de Enfermagem da U S P · 2026Article
- Coping with COVID-19 Intensive Care Unit admission.Revista brasileira de enfermagem · 2026Article
- Musculoskeletal Sequelae of Post-COVID-19 Syndrome: A Systematic Review.Diseases (Basel, Switzerland) · 2025Review
- The economic burden of COVID-19 in a region with stringent response measures: A case study of Taiwan.Journal of food and drug analysis · 2025Article
- Post-COVID-19 functional status in socioeconomically vulnerable neighborhoods attended in primary health care in two Brazilian cities: a cross-sectional study.BMC infectious diseases · 2025Article
- Article
- Post-COVID-19 syndrome and health-related quality of life after hospital discharge.Revista de saude publica · 2025Article
- Inequities in COVID-19 morbidity in Brazil: the influence of demographic and socioeconomic characteristics and preexisting health conditions.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2025Article
- Persistent obstacles for return to work after COVID-19 infection - an explorative follow-up study in Sweden.Frontiers in rehabilitation sciences · 2025Article
- Cost-Utility Analysis of Supervised Inspiratory Muscle Training Added to Post-COVID Rehabilitation Program in the Public Health System of Brazil.International journal of environmental research and public health · 2024Article
- [Post-COVID-19 conditions in the Brazilian Unified National Health System: exploring the uncertain terrain of identification and coping].Cadernos de saude publica · 2024Article
- Long COVID challenges in Brazil: an unfinished agenda for the Brazilian Unified National Health System.Cadernos de saude publica · 2024Article
- Risk factors for post-COVID-19 condition: A case-control study in municipalities of Paraíba and Rio de Janeiro, Brazil.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious DiseasesArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The persistent symptoms of post-COVID-19 syndrome negatively impact health, quality of life, and productivity. This study aimed to describe the persistent symptoms of post-COVID-19 syndrome (especially neurological ones) and their 12-month post-infection cognitive, emotional, motor, quality of life, and indirect cost repercussions. Patients showing the first symptoms of COVID-19 from January to June 2021 who developed post-COVID-19 syndrome and sought care at the Fortaleza Unit (Ceará, Brazil) of the SARAH Network of Rehabilitation Hospitals were included in this study. Information was obtained at the baseline follow-up and by telephone interview 12 months post-infection. In total, 58 people participated in this study with an average age of 52.8±10.5 years, of which 60% required an ICU. The most frequent symptoms on admission included fatigue (64%), arthralgia (51%), and dyspnea (47%), whereas, after 12 months, fatigue (46%) and memory impairment (39%). The following scales/functional tests showed alterations: PCFS, MoCA, HAD, FSS, SF-36, TLS5x, timed up and go, 6-minute walk, and handgrip. Indirect costs totaled USD 227,821.00, with 11,653 days of absenteeism. Moreover, 32% of patients were unable to return to work. Better TLS5x and higher SF-36 scores in the functional capacity, physical functioning, vitality, and pain dimensions were associated with return to work (p ≤ 0.05). The most frequent persistent symptoms referred to fatigue, arthralgia, dyspnea, anxiety, and depression, which negatively affected cognitive, emotional, and motor function and quality of life. These symptoms lasted for over a year, especially fatigue and memory alteration, the latter of which being the most reported after COVID-19 infections. Results also show a significant difficulty returning to work and indirect costs of USD 4,847.25 per person/year.
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