Evidence map›Paper›PMID 38381828›Full record

ArticleScience advances2024

Terpenoid balance in

Sung Chul Park, Breanne N Steffan, Fang Yun Lim, Raveena Gupta, Fatma Ayaloglu Butun, Hongyu Chen, Rosa Ye, Timothy Decker, Chengcang C Wu, Neil L Kelleher and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Leaderless RiPPs expand the repertoire of fungal secondary metabolites.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Sung Chul ParkDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0009-0008-9081-7992
Breanne N SteffanDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0001-7569-4543
Fang Yun LimDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0001-7406-2317
Raveena GuptaDepartment of Chemistry, Northwestern University, Evanston, IL, USA.
Fatma Ayaloglu ButunDepartment of Chemistry, Northwestern University, Evanston, IL, USA.ORCID 0000-0002-4745-8129
Hongyu ChenIntact Genomics Inc., St. Louis, MO, USA.
Rosa YeIntact Genomics Inc., St. Louis, MO, USA.ORCID 0009-0004-5801-9246
Timothy DeckerIntact Genomics Inc., St. Louis, MO, USA.
Chengcang C WuIntact Genomics Inc., St. Louis, MO, USA.
Neil L KelleherDepartment of Chemistry, Northwestern University, Evanston, IL, USA.ORCID 0000-0002-8815-3372
Jin Woo BokDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-4394-2749
Nancy P KellerDepartment of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, WI, USA.ORCID 0000-0002-4386-9473
University of Wisconsin–Madison · USIntact Genomics (United States) · USNorthwestern University · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
NMR User Program at NMRFAMR24GM141526 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Katherine Anne Henzler-Wildman · 2021 to 2026
$6.4M
Mass Spectrometric Studies of Thiotemplate BiosynthesisR01AT009143 · NCCIH · NORTHWESTERN UNIVERSITY · PI NEIL L KELLEHER, NANCY P KELLER · 2016 to 2026
$4.2M
Rapid discovery of thousands of intact biosynthetic gene pathways for bioactive natural product compounds from un-sequenced filamentous fungi using a novel FAC-NGS toolR44AI140943 · NIAID · INTACT GENOMICS, INC. · PI BOK, JIN WOO, CROFTS, TERENCE SPENCER · 2019 to 2022
$3.3M
Comprehensive analysis of NRPS-derived metabolomes of three Aspergillus speciesR01GM112739 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI KELLER, NANCY P · 2015 to 2023
$2.8M
Bidirectional paracrine signaling in the establishment of invasive aspergillosisR01AI150669 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KELLER, NANCY P · 2021 to 2025
$2.4M
Bidirectional paracrine signaling in the establishment of invasive aspergillosisR56AI150669 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KELLER, NANCY P · 2020 to 2020
$466k
ACQUISITION OF MASS SPECTROMETER FOR CORE FACILITYS10RR013790 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI RAINES, RONALD T · 1999 to 1999
–
NCCIH NIH HHS R01 AT009143NCI NIH HHS P30 CA014520NCRR NIH HHS S10 RR013790NIAID NIH HHS R01 AI150669NIAID NIH HHS R44 AI140943NIAID NIH HHS R56 AI150669NIGMS NIH HHS R01 GM112739NIGMS NIH HHS R24 GM141526
6 · The paper itself

Abstract

Filamentous fungi produce numerous uncharacterized natural products (NPs) that are often challenging to characterize because of cryptic expression in laboratory conditions. Previously, we have successfully isolated novel NPs by expressing fungal artificial chromosomes (FACs) from a variety of fungal species into

Indexed as

Aspergillus nidulansPolyisoprenyl PhosphatesSesquiterpenesFarnesyl-Diphosphate FarnesyltransferaseSqualeneTerpenesFarnesyl-Diphosphate Farnesyltransferasefarnesyl pyrophosphatePolyisoprenyl PhosphatesSesquiterpenesSqualeneTerpenes

Identifiers

PMID38381828
PMCPMC10881027
OpenAlexW4391992642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.