Evidence map›Paper›PMID 38381779›Full record

ArticleJBRA assisted reproduction2024

Vitamin D and follicular recruitment in the in vitro fertilization cycle.

Roberto de A Antunes, Brenda M L de Melo, Maria do Carmo B de Souza, Marcelo M de Souza, Gabriela P S Melo, Thamires F M Jandre, Ana Cristina A Mancebo, Flavia L Conceição, Tania M Ortiga-Carvalho

Open access · bronzeAbstract read
In one paragraph

Article in JBRA assisted reproduction, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Roberto de A AntunesGynecology Department of the Clementino Fraga Filho University Hospital - Federal University of Rio de Janeiro - Rio de Janeiro - RJ, Brazil.
Brenda M L de MeloGynecology Department of the Clementino Fraga Filho University Hospital - Federal University of Rio de Janeiro - Rio de Janeiro - RJ, Brazil.
Maria do Carmo B de SouzaFertipraxis - Human Reproduction Center, Rio de Janeiro - RJ, Brazil.
Marcelo M de SouzaFertipraxis - Human Reproduction Center, Rio de Janeiro - RJ, Brazil.
Gabriela P S MeloGynecology Department of the Clementino Fraga Filho University Hospital - Federal University of Rio de Janeiro - Rio de Janeiro - RJ, Brazil.
Thamires F M JandreGynecology Department of the Clementino Fraga Filho University Hospital - Federal University of Rio de Janeiro - Rio de Janeiro - RJ, Brazil.
Ana Cristina A ManceboFertipraxis - Human Reproduction Center, Rio de Janeiro - RJ, Brazil.
Flavia L ConceiçãoEndocrinology Department of the Clementino Fraga Filho University Hospital Federal University of Rio de Janeiro - Rio de Janeiro - RJ, Brazil.
Tania M Ortiga-CarvalhoTranslational Endocrinology Lab of the Carlos Chagas Filho, Biophysics Institute - Federal University of Rio de Janeiro - Rio de Janeiro - RJ, Brazil.
Hospital Universitário Clementino Fraga Filho · BRUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveVitamin D (VD) is a fat-soluble steroid hormone, synthesized by the skin, most known for its role in bone mineral balance. Vitamin D receptors (VDR) are also found in the female reproductive system, but their role remains unclear. The objective of this study was to analyze the relationship between serum vitamin D levels and the number of oocytes retrieved after ovarian stimulation.

methodsThis is a retrospective study involving 267 patients undergoing in vitro fertilization (IVF) carried out in the Fertipraxis clinic, a private practice facility. The patients were initially divided into two groups according to their VD levels. Group 1 included 152 patients with VD levels < 30 ng/mL and group 2 had 115 patients with VD levels > 30 ng/mL. They were further analyzed and separated considering their age, anthropometric data, ovarian reserve, amount of gonadotropin used, and follicles obtained until trigger day.

resultsIn our analysis, there were no difference in the number of follicles and oocytes retrieved, nor in the number of mature oocytes obtained from patients with both vitamin D deficiency and sufficiency.

conclusionsThe results of our study show no difference among number of follicles, oocytes retrieved and mature oocytes obtained after ovarian stimulation according to their vitamin D serum levels. Further higher-quality studies are needed to evaluate the possible roles of serum vitamin D levels in other stages of human fertilization process.

Indexed as

Fertilization in VitroOvarian FollicleOvulation InductionVitamin DAdultFemaleHumansOocyte RetrievalOocytesRetrospective StudiesVitamin Dfollicular developmentinfertilityin vitro fertilizationvitamin D

Identifiers

PMID38381779
PMCPMC11152436
OpenAlexW4391854782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.