Evidence map›Paper›PMID 38381133›Full record

ArticleeLife2024

Energetics of the microsporidian polar tube invasion machinery.

Ray Chang, Ari Davydov, Pattana Jaroenlak, Breane Budaitis, Damian C Ekiert, Gira Bhabha, Manu Prakash

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Cryo-ET reveals the in situ architecture of the polar tube invasion apparatus from microsporidian parasites.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ray ChangDepartment of Bioengineering, Stanford University, Stanford, United States.ORCID 0000-0002-9502-3306
Ari DavydovDepartment of Cell Biology, New York University School of Medicine, New York, United States.
Pattana JaroenlakDepartment of Cell Biology, New York University School of Medicine, New York, United States.
Breane BudaitisDepartment of Cell Biology, New York University School of Medicine, New York, United States.
Damian C EkiertDepartment of Cell Biology, New York University School of Medicine, New York, United States.
Gira BhabhaDepartment of Cell Biology, New York University School of Medicine, New York, United States.
Manu PrakashDepartment of Bioengineering, Stanford University, Stanford, United States.ORCID 0000-0002-8046-8388

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1M
Unravelling lipid trafficking for the bacterial outer membraneR35GM128777 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Damian Ekiert · 2018 to 2026
$4.1M
Structural basis of the polar tube invasion machinery from microsporidia parasitesR01AI147131 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BHABHA, GIRA · 2020 to 2024
$3.4M
Scanning Electron Microscope with 3ViewS10OD019974 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LIANG, FENGXIA · 2016 to 2016
$1.1M
Howard Hughes Medical Institute HHMI Faculty fellowshipNCI NIH HHS P30 CA016087NIAID NIH HHS R01 AI147131NIGMS NIH HHS R35 GM128777NIGMS NIH HHS R35GM128777NIH HHS S10 OD019974
6 · The paper itself

Abstract

Microsporidia are eukaryotic, obligate intracellular parasites that infect a wide range of hosts, leading to health and economic burdens worldwide. Microsporidia use an unusual invasion organelle called the polar tube (PT), which is ejected from a dormant spore at ultra-fast speeds, to infect host cells. The mechanics of PT ejection are impressive.

Indexed as

Anatomy, RegionalCell NucleusBiophysicscellular hydraulicsinfectious diseasemicrobiologymicrosporidiaphysics of living systemsultrafast biophysics

Identifiers

PMID38381133
PMCPMC10942582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.