Evidence map›Paper›PMID 38380696›Full record

ArticleAddiction biology2024

Towards a replacement therapy for stimulant betel quid dependence: A proof of concept study.

Peter G Osborne, Ragavendra Rao Pasupuleti, Chien-Hung Lee, Vinoth Kumar Ponnusamy

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Addiction biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Peter G OsborneBaongong Agriscience Center, Fengtian, Taiwan.ORCID 0000-0003-0942-8444
Ragavendra Rao PasupuletiDepartment of Medicinal and Applied Chemistry, Kaohsiung Medical University (KMU), Kaohsiung City, Taiwan.
Chien-Hung LeeResearch Center for Precision Environmental Medicine, Kaohsiung Medical University (KMU), Kaohsiung City, Taiwan.
Vinoth Kumar PonnusamyDepartment of Medicinal and Applied Chemistry, Kaohsiung Medical University (KMU), Kaohsiung City, Taiwan.
Kaohsiung Medical University · TWCorteva (United States) · USNational Kaohsiung First University of Science and Technology · TW

Funding

Research Center for Environmental Medicine, Kaohsiung Medical University from the Featured Areas Research Center Program within the framework of the Higher Education Sprout Project by the Taiwan Ministry of Education KMU-TC111A01Research Center for Environmental Medicine, Kaohsiung Medical University from the Featured Areas Research Center Program within the framework of the Higher Education Sprout Project by the Taiwan Ministry of Education KMU-TC111IFSP01
6 · The paper itself

Abstract

Stimulant betel quid (SBQ) containing Piper betle leaf (L), green unripe Areca catechu nut (AN) and the alkalizing agent, slaked lime, is an addictive, carcinogenic stimulant, with no pharmacotherapy, chewed by millions of people in the Asia/Pacific region. We compared the in vivo physiological profile of chewing (1) non-stimulant P. betle leaf+AN (LAN), (2) SBQ utilizing slaked lime and (3) a novel SBQ utilizing Mg(OH)

Indexed as

ArecaOxidesTandem Mass SpectrometryCalcium CompoundsHumansProof of Concept StudyCalcium CompoundslimeOxidesaddictionAreca CatechudependenceMg(OH)2Oral cancerUHPLC-MS/MS

Identifiers

PMID38380696
PMCPMC10898838
OpenAlexW4391613255

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.