Evidence map›Paper›PMID 38380564›Full record

ArticleDigestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society2025

Effectiveness of endoscopic ultrasound (EUS)-guided choledochoduodenostomy vs. EUS-guided gallbladder drainage for jaundice in patients with malignant distal biliary obstruction after failed endoscopic retrograde cholangiopancreatography: Retrospective, multicenter study (GALLBLADEUS Study).

Antoine Debourdeau, Jules Daniel, Ludovic Caillo, Eric Assenat, Martin Bertrand, Thomas Bardol, François-Régis Souche, Philippe Pouderoux, Romain Gerard, Diane Lorenzo and 1 more

Open access · hybridAbstract readMulticenter StudyComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Observational
  6. Role of Endoscopy in Malignant Biliary Obstruction.Diagnostics (Basel, Switzerland) · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Endoscopic ultrasound-guided gallbladder drainage for acute cholecystitis.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025
    Review
  17. Endoscopic ultrasound-guided gallbladder drainage for jaundice: Response to Vanella et al.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025
    Article
  18. Review
  19. Review
  20. Endoscopic ultrasound-guided biliary drainageWorld journal of gastrointestinal surgery · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Antoine Debourdeau *Hepatogastroenterology Department, Nimes University Hospital, University of Montpellier, Nimes, France.ORCID https://orcid.org/0000-0003-3785-6948
Jules Daniel *Hepatogastroenterology Department, Nimes University Hospital, University of Montpellier, Nimes, France.
Ludovic CailloHepatogastroenterology Department, Nimes University Hospital, University of Montpellier, Nimes, France.
Eric AssenatHepatogastroenterology Department, Montpellier University Hospital, University of Montpellier, Montpellier, France.
Martin BertrandSurgery Department, Nimes University Hospital, University of Montpellier, Nimes, France.
Thomas BardolSurgery Department, Montpellier University Hospital, University of Montpellier, Montpellier, France.
François-Régis SoucheSurgery Department, Montpellier University Hospital, University of Montpellier, Montpellier, France.
Philippe PouderouxHepatogastroenterology Department, Nimes University Hospital, University of Montpellier, Nimes, France.
Romain GerardHepatogastroenterology Department, Lille University Hospital, Lille University, Lille, France.
Diane Lorenzo *Hepatogastroenterology Department, Beaujon University Hospital, Paris Cité University, Paris, France.
Jean-François Bourgaux *Hepatogastroenterology Department, Nimes University Hospital, University of Montpellier, Nimes, France.
Université de Montpellier · FRUniversité de Lille · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to compare endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) vs. EUS-gallbladder drainage (EUS-GBD) in cases of failed endoscopic retrograde cholangiopancreatography (ERCP) for jaundice resulting from malignant distal biliary obstruction (MDBO).

methodsThis multicenter retrospective study included patients with obstructive jaundice secondary to MDBO who underwent EUS-GBD or EUS-CDS with lumen-apposing metal stents after failed ERCP. The primary end-point was clinical success rate. Secondary end-points were technical success, periprocedural adverse events rate (<24 h), late adverse events rate (>24 h), overall survival, and time to recurrent biliary obstruction.

resultsA total of 78 patients were included: 41 underwent EUS-GBD and 37 underwent EUS-CDS. MDBO was mainly the result of pancreatic cancer (n = 63/78, 80.7%). Clinical success rate was similar for both procedures: 87.8% for EUS-GBD and 89.2% for EUS-CDS (P = 0.8). Technical success rate was 100% for EUS-GBD and 94.6% for EUS-CDS (P = 0.132). Periprocedural morbidity (<24 h) rates were similar between both groups: 4/41 (9.8%) for EUS-GBD and 5/37 (13.5%) for EUS-CDS (P = 0.368). There was a significantly higher rate of late morbidity (>24 h) among patients in the EUS-CDS group (8/37 [21.6%]) than in the EUS-GBD group (3/41 [7.3%]) (P = 0.042). The median follow-up duration was 4.7 months. Overall survival and time to recurrent biliary obstruction did not significantly differ between the groups. DISCUSSION: After failed ERCP for MDBO, EUS-GBD and EUS-CDS show comparable clinical success rates and technical success. EUS-GBD appears to be a promising alternative for MDBO, even as a second-line treatment after failed ERCP. Further studies are needed to validate these findings and compare the long-term outcomes of EUS-GBD and EUS-CDS.

Indexed as

Cholangiopancreatography, Endoscopic RetrogradeCholedochostomyDrainageEndosonographyJaundice, ObstructiveAgedAged, 80 and overCholestasisFemaleGallbladderHumansMaleMiddle AgedPancreatic NeoplasmsRetrospective StudiesTreatment Failurebiliary drainageendoscopyEUSgallbladderpancreatic cancer

Identifiers

PMID38380564
PMCPMC11718144
OpenAlexW4392013851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.