ArticleInternational journal of epidemiology2024
Time-stratified case-crossover studies for aggregated data in environmental epidemiology: a tutorial.
Article in International journal of epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Building the model: a review of input structures in extreme temperature-health.Environmental health : a global access science source · 2026Pooled it
- Environmental exposures in autoimmune inflammatory rheumatic diseases: a priority-based evidence map, immune-mechanism integration audit and research agenda.Frontiers in immunology · 2026Pooled it
- Two-way fixed effects models in air pollution epidemiology: a proposed framework for model specifications and recommendations for future studies.American journal of epidemiology · 2026Article
- An explainable geospatial framework for fine-scale Fatty Liver Disease (FLD) risk assessment: roles of social economy, built environment, and psychology.BMC public health · 2026Article
- Ambient Air Pollution and Hospital Admissions of AECOPD in 10 Regions of China: A Self-Controlled Study Based on a Cohort.Environment & health (Washington, D.C.) · 2026Article
- Associations between extreme temperatures and hospitalizations among Chinese cancer patients with atrial fibrillation: a case-crossover study.Cardio-oncology (London, England) · 2026Article
- Heat Stress and Placental Abruption: A Space-Time Stratified Case-Crossover Study.BJOG : an international journal of obstetrics and gynaecology · 2026Article
- Spatial heterogeneity in the burden of respiratory syncytial virus infection attributable to low and high ambient temperature in Japan: a nationwide time-stratified case-crossover analysis.Respiratory research · 2026Article
- Motor vehicle crashes during wildfire smoke events in California (2010-2020).American journal of epidemiology · 2026Article
- Sunshine duration and episodes of mental disorders and the inverse effect modification by ambient temperature.BMC medicine · 2026Article
- Data Resource Profile: Climate and Enteric Diseases Research Project (ClimED).International journal of epidemiology · 2026Article
- Modifying effect of statin use on the association between nitrogen dioxide exposure and ischemic heart disease in patients with hypertension.Clinical hypertension · 2026Article
- Environmental drivers of vertigo.Environmental health and preventive medicine · 2026Article
- Extreme heat disproportionately increases severe road traffic crashes in high conflict settings and among vulnerable road users in California.Discover cities · 2026Article
- The overlapping impacts of heat and COVID-19 on mortality in Flanders, Belgium: a time-stratified case-crossover analysis.Scientific reports · 2025Article
- Risk of hospitalization and mortality across US climate regions following extreme heat exposure in patients with end-stage kidney disease (ESKD) receiving in-center hemodialysis: a space-time-stratified case-crossover analysis.Environmental health : a global access science source · 2025Article
- Extreme Heat, Social Factors, and Mortality Among California Veterans With Cardiometabolic Disease.JAMA network open · 2025Article
- Ambient temperature and non-accidental mortality: A nationwide space-time-stratified case-crossover study within the 100 million Brazilian Cohort.Environment international · 2025Article
- Short-Term Effect of Air Pollution on Out of Hospital Cardiac Arrest (OHCA) in Lombardy-A Case-Crossover Spatiotemporal Study.Global challenges (Hoboken, NJ) · 2025Article
- Health impacts of extreme heat in medically at-risk populations: a space-time stratified case-crossover analysis in Belgium.BMC public health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The case-crossover design is widely used in environmental epidemiology as an effective alternative to the conventional time-series regression design to estimate short-term associations of environmental exposures with a range of acute events. This tutorial illustrates the implementation of the time-stratified case-crossover design to study aggregated health outcomes and environmental exposures, such as particulate matter air pollution, focusing on adjusting covariates and investigating effect modification using conditional Poisson regression. Time-varying confounders can be adjusted directly in the conditional regression model accounting for the adequate lagged exposure-response function. Time-invariant covariates at the subpopulation level require reshaping the typical time-series data set into a long format and conditioning out the covariate in the expanded stratum set. When environmental exposure data are available at geographical units, the stratum set should combine time and spatial dimensions. Moreover, it is possible to examine effect modification using interaction models. The time-stratified case-crossover design offers a flexible framework to properly account for a wide range of covariates in environmental epidemiology studies.
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