Evidence map›Paper›PMID 38380336›Full record

ArticleMaterials advances2024

Melanoma immunotherapy enabled by M2 macrophage targeted immunomodulatory cowpea mosaic virus.

Zhongchao Zhao, Young Hun Chung, Nicole F Steinmetz

Open access · goldAbstract read
In one paragraph

Article in Materials advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Plant-Derived Anti-Cancer Therapeutics and Biopharmaceuticals.Bioengineering (Basel, Switzerland) · 2024
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zhongchao ZhaoDepartment of NanoEngineering, University of California 9500 Gilman Dr, La Jolla San Diego CA 92093 USA nsteinmetz@ucsd.edu.ORCID https://orcid.org/0000-0002-3736-6677
Young Hun ChungMoores Cancer Center, University of California 9500 Gilman Dr, La Jolla San Diego CA 92093 USA.ORCID https://orcid.org/0000-0002-6578-8076
Nicole F SteinmetzDepartment of NanoEngineering, University of California 9500 Gilman Dr, La Jolla San Diego CA 92093 USA nsteinmetz@ucsd.edu.ORCID https://orcid.org/0000-0002-0130-0481
University of California San Diego · US

Funding

Bioprinting Plant Virus Nanoparticles for Immunotherapy and Relapse Prevention of Ovarian CancerR01CA253615 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHEN, SHAOCHEN, FIERING, STEVEN · 2020 to 2024
$3.1M
NCI NIH HHS R01 CA253615
6 · The paper itself

Abstract

We have developed nanoparticle formulations targeting M2 macrophages for cancer immunotherapy by conjugating high-affinity binding peptides to cowpea mosaic virus as an immunostimulatory adjuvant. We confirmed the targeting of and uptake by M2 macrophages

Identifiers

PMID38380336
PMCPMC10876082
OpenAlexW4391252845

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.