Evidence map›Paper›PMID 38379915›Full record

ReviewClinical ophthalmology (Auckland, N.Z.)2024

Glucocorticoid-Induced Ocular Hypertension and Glaucoma.

Devon Hori Harvey, Chenna Kesavulu Sugali, Weiming Mao

Open access · goldAbstract readReview
In one paragraph

Review in Clinical ophthalmology (Auckland, N.Z.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Devon Hori HarveyDepartment of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN, USA.
Chenna Kesavulu SugaliDepartment of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN, USA.
Weiming MaoDepartment of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN, USA.
Hypertension Institute · US

Funding

The role of Wnt signaling in treating glucocorticoid-induced glaucomaR01EY031700 · NEI · INDIANA UNIVERSITY INDIANAPOLIS · PI MAO, WEIMING · 2021 to 2025
$2.5M
Cross-talk between TGF-beta and Wnt pathways in the trabecular meshworkR01EY026962 · NEI · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI MAO, WEIMING · 2017 to 2021
$1.9M
The role of distal aqueous humor outflow tissue in glucocorticoid-induced glaucomaR21EY033929 · NEI · INDIANA UNIVERSITY INDIANAPOLIS · PI MAO, WEIMING · 2023 to 2024
$436k
Identification of genes responsible for glucocorticoid-induced glaucomaR21EY023048 · NEI · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI MAO, WEIMING · 2013 to 2014
$388k
NEI NIH HHS R01 EY026962NEI NIH HHS R01 EY031700NEI NIH HHS R21 EY023048NEI NIH HHS R21 EY033929
6 · The paper itself

Abstract

Glucocorticoid (GC) therapy is indicated in many diseases, including ocular diseases. An important side-effect of GC therapy is GC-induced ocular hypertension (GIOHT), which may cause irreversible blindness known as GC-induced glaucoma (GIG). Here, we reviewed the pathological changes that contribute to GIOHT including in the trabecular meshwork and Schlemm's canal at cellular and molecular levels. We also discussed the clinical aspects of GIOHT/GIG including disease prevalence, risk factors, the type of GCs, the route of GC administration, and management strategies.

Indexed as

aqueous humor outflowglucocorticoidintraocular pressuremechanismtrabecular meshworktreatment

Identifiers

PMID38379915
PMCPMC10878139
OpenAlexW4391886831

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.