Evidence map›Paper›PMID 38379913›Full record

ArticleFrontiers in pediatrics2024

Airway opening pressure maneuver to detect airway closure in mechanically ventilated pediatric patients.

Luciana Rodriguez Guerineau, Fernando Vieira, Antenor Rodrigues, Katherine Reise, Mark Todd, Anne-Marie Guerguerian, Laurent Brochard

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07262541 (Assessment of Airway Opening Pressure in Invasively Ventilated Children), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07262541 narecruitingnot on this mapstarted 2026, after this paper: background citation

Assessment of Airway Opening Pressure in Invasively Ventilated Children

TypeinterventionalSponsorAssistance Publique - Hôpitaux de ParisRan2026 to 2031Enrolled50ConditionsAcute Respiratory Distress Syndrome in ChildrenArmsMeasurement of airway opening pressure
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luciana Rodriguez GuerineauDepartment of Critical Care Medicine, Hospital for Sick Children, Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.
Fernando VieiraKeenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.
Antenor RodriguesKeenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.
Katherine ReiseDepartment of Respiratory Therapy and Critical Care Medicine, Hospital for Sick Children, Toronto, ON, Canada.
Mark ToddDepartment of Respiratory Therapy and Critical Care Medicine, Hospital for Sick Children, Toronto, ON, Canada.
Anne-Marie GuerguerianDepartment of Critical Care Medicine, Hospital for Sick Children, Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.
Laurent BrochardKeenan Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Airway closure, which refers to the complete collapse of the airway, has been described under mechanical ventilation during anesthesia and more recently in adult patients with acute respiratory distress syndrome (ARDS). A ventilator maneuver can be used to identify airway closure and measure the pressure required for the airway to reopen, known as the airway opening pressure (AOP). Without that maneuver, AOP is unknown to clinicians. Objective: This study aims to demonstrate the technical adaptation of the adult maneuver for children and illustrate its application in two cases of pediatric ARDS (p-ARDS). Methods: A bench study was performed to adapt the maneuver for 3-50 kg patients. Four maneuvers were performed for each simulated patient, with 1, 2, 3, and 4 s of insufflation time to deliver a tidal volume (Vt) of 6 ml/kg by a continuous flow. Results: Airway closure was simulated, and AOP was visible at 15 cmH Conclusions: We propose a pediatric AOP maneuver delivering 6 ml/kg of Vt at a continuous low-flow inflation for 3 s for patients weighing up to 20 kg and for 4 s for patients weighing beyond 20 kg.

Indexed as

acute respiratory distress syndromeairway closureairway opening pressure maneuverpediatricsrespiratory maneuvers

Identifiers

PMID38379913
PMCPMC10877025

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