Evidence map›Paper›PMID 38379830›Full record

ArticleBio-protocol2024

Quantification of Macrophage Cellular Ferrous Iron (Fe

Philipp Grubwieser, Natascha Brigo, Markus Seifert, Manuel Grander, Igor Theurl, Manfred Nairz, Günter Weiss, Christa Pfeifhofer-Obermair

Open access · diamondAbstract read
In one paragraph

Article in Bio-protocol, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Loss of NR2F6 Protects from Salmonella Typhimurium Infection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  8. NIR-responsive CuJournal of nanobiotechnology · 2025
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Philipp GrubwieserDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Natascha BrigoDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Markus SeifertDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Manuel GranderDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Igor TheurlDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Manfred NairzDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Günter WeissDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Christa Pfeifhofer-ObermairDepartment of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria.
Innsbruck Medical University · ATUniversität Innsbruck · AT

Funding

Austrian Science Fund FWF DOC 82
6 · The paper itself

Abstract

Macrophages are at the center of innate immunity and iron metabolism. In the case of an infection, macrophages adapt their cellular iron metabolism to deprive iron from invading bacteria to combat intracellular bacterial proliferation. A concise evaluation of the cellular iron content upon an infection with bacterial pathogens and diverse cellular stimuli is necessary to identify underlying mechanisms concerning iron homeostasis in macrophages. For the characterization of cellular iron levels during infection, we established an in vitro infection model where the murine macrophage cell line J774A.1 is infected with

Indexed as

FerroOrangeFluorescenceIronIron quantificationMacrophagesSalmonella Typhimurium

Identifiers

PMID38379830
PMCPMC10875354
OpenAlexW4390587232

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.