Evidence map›Paper›PMID 38379818›Full record

ArticleFrontiers in surgery2024

Differences in surgical outcomes between cervical goiter and retrosternal goiter: an international, multicentric evaluation.

Federico Cappellacci, Gian Luigi Canu, Leonardo Rossi, Andrea De Palma, Maria Mavromati, Paulina Kuczma, Giacomo Di Filippo, Eleonora Morelli, Marco Stefano Demarchi, Paolo Brazzarola and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Surgical approaches to the management of the intrathoracic goiter - A systematic review.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2025
    Pooled it
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Federico CappellacciDepartment of Surgical Sciences, University of Cagliari, Cagliari, Italy.
Gian Luigi CanuDepartment of Surgical Sciences, University of Cagliari, Cagliari, Italy.
Leonardo RossiEndocrine Surgery Unit, University Hospital of Pisa, Pisa, Italy.
Andrea De PalmaEndocrine Surgery Unit, University Hospital of Pisa, Pisa, Italy.
Maria MavromatiService D'endocrinologie, Diabétologie, Nutrition et éducation du Patient, Hôpitaux Universitaires de Genève, Genève, Switzerland.
Paulina KuczmaDepartment of Thoracic and Endocrine Surgery and Faculty of Medicine, University Hospitals of Geneva, Geneva, Switzerland.
Giacomo Di FilippoEndocrine Surgery Unit, Department of Surgery and Oncology, University and Hospital Trust of Verona, Verona, Italy.
Eleonora MorelliEndocrine Surgery Unit, Department of Surgery and Oncology, University and Hospital Trust of Verona, Verona, Italy.
Marco Stefano DemarchiDepartment of Thoracic and Endocrine Surgery and Faculty of Medicine, University Hospitals of Geneva, Geneva, Switzerland.
Paolo BrazzarolaEndocrine Surgery Unit, Department of Surgery and Oncology, University and Hospital Trust of Verona, Verona, Italy.
Gabriele MaterazziEndocrine Surgery Unit, University Hospital of Pisa, Pisa, Italy.
Pietro Giorgio CalòDepartment of Surgical Sciences, University of Cagliari, Cagliari, Italy.
Fabio MedasDepartment of Surgical Sciences, University of Cagliari, Cagliari, Italy.
our Mediastinal Goiter Study Collaborative Group
University of Cagliari · ITAzienda Ospedaliera Universitaria Pisana · ITUniversity of Verona · ITUniversity Hospital of Geneva · CHHôpital Beau-Séjour · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Goiter is a common problem in clinical practice, representing a large part of clinical evaluations for thyroid disease. It tends to grow slowly and progressively over several years, eventually occupying the thoracic inlet with its lower portion, defining the situation known as retrosternal goiter. Total thyroidectomy is a standardized procedure that represents the treatment of choice for all retrosternal goiters, but when is performed for such disease, a higher risk of postoperative morbidity is variously reported in the literature. The aims of our study were to compare the perioperative and postoperative outcomes in patients with cervical goiters and retrosternal goiters undergoing total thyroidectomy. Methods: In our retrospective, multicentric evaluation we included 4,467 patients, divided into two groups based on the presence of retrosternal goiter (group A) or the presence of a classical cervical goiter (group B). Results: We found statistically significant differences in terms of transient hypoparathyroidism (19.9% in group A vs. 9.4% in group B, Discussion: Wound infection rate was higher in group A compared to group B (1.4% in group A vs. 0.2% in group B,

Indexed as

cervicomediastinal goitermediastinal goiterretrosternal goiterthyroid surgerythyroid surgery morbidity

Identifiers

PMID38379818
PMCPMC10876881
OpenAlexW4391568226

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.