Evidence map›Paper›PMID 38379763›Full record

ArticleFrontiers in neuroscience2024

Genetic mechanisms underlying local spontaneous brain activity in episodic migraine.

Wei Gui, Fengqing Lu, Lulan Fu, Ziru Deng, Xiuxiu Zhao, Wenwen Cheng, Ying Yang, Yu Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Wei GuiDepartment of Neurology, Epilepsy and Headache Group, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Fengqing LuDepartment of Neurology, Epilepsy and Headache Group, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Lulan FuDepartment of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Ziru DengDepartment of Neurology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Xiuxiu ZhaoAnhui Provincial Stereotactic Neurosurgical Institute, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine University of Science and Technology of China, Hefei, China.
Wenwen ChengAnhui Provincial Stereotactic Neurosurgical Institute, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine University of Science and Technology of China, Hefei, China.
Ying Yang *Department of Radiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine University of Science and Technology of China, Hefei, China.
Yu Wang *Department of Neurology, Epilepsy and Headache Group, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
University of Science and Technology of China · CNAnhui Medical University · CNFirst Affiliated Hospital of Anhui Medical University · CNSecond Affiliated Hospital of Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in neuroimaging techniques during the past few decades have captured impaired functional brain activity in migraine disorders, yet the molecular mechanisms accounting for its alterations in migraine remain largely unknown. A total of 27 patients with episodic migraine (EM) and 30 matched healthy controls (HCs) underwent resting-state functional and structural magnetic resonance imaging (MRI) scans. Regional homogeneity (ReHo), low-frequency fluctuations (ALFF), and fractional amplitude of low-frequency fluctuations (fALFF) of fMRI were compared between the two groups. Based on the Allen Human Brain Atlas and risk genes in migraine, we identified gene expression profiles associated with ReHo alterations in EM. Compared with HCs, patients with EM showed increased ReHo in the left orbital part of the superior frontal gyrus (

Indexed as

Allen Human Brain Atlasfunctional MRIgenemigraineregional homogeneity

Identifiers

PMID38379763
PMCPMC10876778
OpenAlexW4391571473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.