Evidence map›Paper›PMID 38378773›Full record

ArticleNPJ precision oncology2024

Machine learning and radiomics for segmentation and classification of adnexal masses on ultrasound.

Jennifer F Barcroft, Kristofer Linton-Reid, Chiara Landolfo, Maya Al-Memar, Nina Parker, Chris Kyriacou, Maria Munaretto, Martina Fantauzzi, Nina Cooper, Joseph Yazbek and 9 more

Abstract read
In one paragraph

Article in NPJ precision oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Developing and validating ultrasound-based machine-learning models incorporating radiomics features to predict malignancy in adnexal masses.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026
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  12. Multimodal ultrasound-based radiomics and deep learning for differential diagnosis of O-RADS 4-5 adnexal masses.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Jennifer F Barcroft *Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Kristofer Linton-Reid *Department of Surgery and Cancer, Imperial College London, London, UK.
Chiara LandolfoDepartment of Obstetrics and Gynaecology, Imperial College Healthcare NHS Trust, London, UK.
Maya Al-MemarDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Nina ParkerDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Chris KyriacouDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Maria MunarettoDepartment of Obstetrics and Gynaecology, Ospedale Morgagni-Pierantoni, Forli, Italy.
Martina FantauzziDepartment of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy.ORCID http://orcid.org/0000-0002-9795-5246
Nina CooperDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Joseph YazbekDepartment of Obstetrics and Gynaecology, Imperial College Healthcare NHS Trust, London, UK.
Nishat BharwaniDepartment of Radiology, Imperial College Healthcare NHS Trust, London, UK.ORCID http://orcid.org/0000-0002-6236-1480
Sa Ra LeeDepartment of Obstetrics and Gynaecology, Asan Medical Center, Seoul, South Korea.
Ju Hee KimDepartment of Obstetrics and Gynaecology, Asan Medical Center, Seoul, South Korea.
Dirk TimmermanDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Joram PosmaDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.ORCID http://orcid.org/0000-0002-4971-9003
Luca SavelliDepartment of Obstetrics and Gynaecology, Ospedale Morgagni-Pierantoni, Forli, Italy.
Srdjan SasoDepartment of Obstetrics and Gynaecology, Imperial College Healthcare NHS Trust, London, UK.
Eric O AboagyeDepartment of Surgery and Cancer, Imperial College London, London, UK. eric.aboagye@imperial.ac.uk.ORCID http://orcid.org/0000-0003-2276-6771
Tom BourneDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.

Funding

RCUK | MRC | Medical Research Foundation MR/M015858/1
6 · The paper itself

Abstract

Ultrasound-based models exist to support the classification of adnexal masses but are subjective and rely upon ultrasound expertise. We aimed to develop an end-to-end machine learning (ML) model capable of automating the classification of adnexal masses. In this retrospective study, transvaginal ultrasound scan images with linked diagnoses (ultrasound subjective assessment or histology) were extracted and segmented from Imperial College Healthcare, UK (ICH development dataset; n = 577 masses; 1444 images) and Morgagni-Pierantoni Hospital, Italy (MPH external dataset; n = 184 masses; 476 images). A segmentation and classification model was developed using convolutional neural networks and traditional radiomics features. Dice surface coefficient (DICE) was used to measure segmentation performance and area under the ROC curve (AUC), F1-score and recall for classification performance. The ICH and MPH datasets had a median age of 45 (IQR 35-60) and 48 (IQR 38-57) years old and consisted of 23.1% and 31.5% malignant cases, respectively. The best segmentation model achieved a DICE score of 0.85 ± 0.01, 0.88 ± 0.01 and 0.85 ± 0.01 in the ICH training, ICH validation and MPH test sets. The best classification model achieved a recall of 1.00 and F1-score of 0.88 (AUC:0.93), 0.94 (AUC:0.89) and 0.83 (AUC:0.90) in the ICH training, ICH validation and MPH test sets, respectively. We have developed an end-to-end radiomics-based model capable of adnexal mass segmentation and classification, with a comparable predictive performance (AUC 0.90) to the published performance of expert subjective assessment (gold standard), and current risk models. Further prospective evaluation of the classification performance of this ML model against existing methods is required.

Identifiers

PMID38378773
PMCPMC10879532

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.