Evidence map›Paper›PMID 38378585›Full record

ArticleBMJ case reports2024

Treatment of metastatic rectal squamous cell carcinoma in a pregnant patient.

Nathan S Kau, Jeannie C Kelly, Hyun Kim, Radhika Smith, Tyler J Fraum, Kathleen Byrnes, Nikolaos A Trikalinos, Olivia Aranha, Kevin Z Li, Shiyuan Anabeth Liu and 1 more

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Nathan S KauDepartment of Medicine, Division of Medical Oncology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA nathan.kau@wustl.edu.ORCID http://orcid.org/0000-0003-0491-6641
Jeannie C KellyDepartment of Obstetrics and Gynecology, Washington University in St Louis School of Medicine, St Louis, Missouri, USA.
Hyun KimDepartment of Radiation Oncology, Washington University in St Louis School of Medicine, St Louis, Missouri, USA.
Radhika SmithDepartment of Surgery, Division of Colon and Rectal Surgery, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Tyler J FraumDepartment of Radiology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Kathleen ByrnesDepartment of Pathology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Nikolaos A TrikalinosDepartment of Medicine, Division of Medical Oncology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Olivia AranhaDepartment of Medicine, Division of Medical Oncology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Kevin Z LiDepartment of Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Shiyuan Anabeth LiuDepartment of Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Rama SureshDepartment of Medicine, Division of Medical Oncology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Washington University in St. Louis · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
NCATS NIH HHS UL1 TR002345
6 · The paper itself

Abstract

Rectal squamous cell carcinoma is an exceedingly rare form of rectal cancer, with limited data available regarding its presentation and effective treatment. Rectal cancer occurring during pregnancy is uncommon as well. This is a case of metastatic rectal squamous cell carcinoma presenting in a 22-week pregnant, female patient in her early 30s. The patient was treated with 5-fluorouracil and cisplatin and delivered a healthy male child born via uncomplicated vaginal delivery at 35 weeks. This article demonstrates that despite the rare nature of this cancer, in the already rare context of pregnancy, effective and safe treatment is possible with a multidisciplinary team.

Indexed as

Carcinoma, Squamous CellRectal NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsChildCisplatinFemaleFluorouracilHumansMalePregnancyTreatment OutcomeCisplatinFluorouracilcancer-see oncologychemotherapycolon cancerpregnancy

Identifiers

PMID38378585
PMCPMC10882350
OpenAlexW4392005143

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.