ArticleMicrobiome2024
Virome diversity shaped by genetic evolution and ecological landscape of Haemaphysalis longicornis.
Article in Microbiome, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 21 citations in OpenAlex.
- Metagenomic insights into pathogen diversity and public health risk of Haemaphysalis longicornis in Gansu Province of China.PLoS neglected tropical diseases · 2026Article
- Tick-borne viruses: discovery, clinical aspects, influencing factors and control.Nature reviews. Microbiology · 2026Review
- Meta-transcriptomic characterization reveals viral species with zoonotic potential in Rhipicephalus microplus and Haemaphysalis bispinosa ticks in Pakistan.Veterinary research · 2026Article
- Genetic diversity of Theileria species identified from questing and parasitic ticks in selected areas in Qinghai, China.Veterinary research communications · 2026Article
- Triploidy drives vector capacity and expansion of the parthenogenetic tick Haemaphysalis longicornis.Communications biology · 2025Article
- Diverse virome and potential pathogens in five tick species from metropolis surroundings of Beijing and Tianjin, China.NPJ biofilms and microbiomes · 2025Article
- Meta-transcriptomic analysis of tick virome diversity and ecological characteristics in Yunnan Province, southwestern China.Virologica Sinica · 2025Article
- First genetic characterization and phylogenetic analysis of Okutama tick virus in a tick collected from a raccoon dog (Nyctereutes procyonoides) in South Korea.Virology journal · 2025Article
- Genome-resolved metagenomics reveals microbiome diversity across 48 tick species.Nature microbiology · 2025Article
- SFTSV Prevalence in Ticks and Livestock in an SFTSV-Endemic Area in Central China.Pathogens (Basel, Switzerland) · 2025Article
- Neonatal mouse model reveals pathogenesis of Shanxi Tick Virus 2 isolated from Haemaphysalis longicornis.Virology journal · 2025Article
- Towards tick virome and emerging tick-borne viruses: Protocols, challenges and perspectives.iMetaOmics · 2025Article
- Sexual epigenetics: genome-wide analysis revealed differential DNA methylation in the vector tick Haemaphysalis longicornis.Parasites & vectors · 2025Article
- Host taxonomy and environment shapes insectivore viromes and viral spillover risks in Southwestern China.Microbiome · 2025Article
- Article
- Virome analysis and detection of ticks and tick-borne viruses in Shanghai, China.Frontiers in microbiology · 2025Article
- Alarming implications: severe fever with thrombocytopenia syndrome and its biological vectors in the context of climate change.Frontiers in microbiology · 2025Review
- Viral Diversity and Ecological Impact of DNA Viruses in Dominant Tick Species in China.Microorganisms · 2024Article
- RNA viromes of Dermacentor nuttalli ticks reveal a novel uukuvirus in Qīnghăi Province, China.Virologica Sinica · 2024Article
- Host Jump of an Exotic Fish Rhabdovirus into a New Class of Animals Poses a Disease Threat to Amphibians.Viruses · 2024Article
Corrections and comments
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Authors and funding
27 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundHaemaphysalis longicornis is drawing attentions for its geographic invasion, extending population, and emerging disease threat. However, there are still substantial gaps in our knowledge of viral composition in relation to genetic diversity of H. longicornis and ecological factors, which are important for us to understand interactions between virus and vector, as well as between vector and ecological elements.
resultsWe conducted the meta-transcriptomic sequencing of 136 pools of H. longicornis and identified 508 RNA viruses of 48 viral species, 22 of which have never been reported. Phylogenetic analysis of mitochondrion sequences divided the ticks into two genetic clades, each of which was geographically clustered and significantly associated with ecological factors, including altitude, precipitation, and normalized difference vegetation index. The two clades showed significant difference in virome diversity and shared about one fifth number of viral species that might have evolved to "generalists." Notably, Bandavirus dabieense, the pathogen of severe fever with thrombocytopenia syndrome was only detected in ticks of clade 1, and half number of clade 2-specific viruses were aquatic-animal-associated.
conclusionsThese findings highlight that the virome diversity is shaped by internal genetic evolution and external ecological landscape of H. longicornis and provide the new foundation for promoting the studies on virus-vector-ecology interaction and eventually for evaluating the risk of H. longicornis for transmitting the viruses to humans and animals. Video Abstract.
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