Evidence map›Paper›PMID 38378022›Full record

ArticleNuklearmedizin. Nuclear medicine2024

Diagnostic accuracy of artificial intelligence-enabled vectorcardiography versus myocardial perfusion SPECT in patients with suspected or known coronary heart disease.

Simon Aydar, Hermann Knobl, Wolfgang Burchert, Oliver Lindner

Abstract readComparative Study
In one paragraph

Article in Nuklearmedizin. Nuclear medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Simon AydarInstitute of Radiology, Nuclearmedicine and Molecular Imaging, Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Germany.
Hermann KnoblInstitute of Radiology, Nuclearmedicine and Molecular Imaging, Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Germany.
Wolfgang BurchertInstitute of Radiology, Nuclearmedicine and Molecular Imaging, Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Germany.
Oliver LindnerInstitute of Radiology, Nuclearmedicine and Molecular Imaging, Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe present study evaluated with myocardial perfusion SPECT (MPS) the diagnostic accuracy of an artificial intelligence-enabled vectorcardiography system (Cardisiography, CSG) for detection of perfusion abnormalities.

methodsWe studied 241 patients, 155 with suspected CAD and 86 with known CAD who were referred for MPS. The CSG was performed after the MPS acquisition. The CSG results (1) p-factor (perfusion, 0: normal, 1: mildly, 2: moderately, 3: highly abnormal) and (2) s-factor (structure, categories as p-factor) were compared with the MPS scores. The CSG system was not trained during the study.

resultsConsidering the p-factor alone, a specificity of >78% and a negative predictive value of mostly >90% for all MPS variables were found. The sensitivities ranged from 17 to 56%, the positive predictive values from 4 to 38%. Combining the p- and the s-factor, significantly higher specificity values of about 90% were reached. The s-factor showed a significant correlation (p=0.006) with the MPS ejection fraction.

conclusionsThe CSG system is able to exclude relevant perfusion abnormalities in patients with suspected or known CAD with a specificity and a negative predictive value of about 90% combining the p- and the s-factor. Since it is a learning system there is potential for further improvement before routine use.

Indexed as

Artificial IntelligenceMyocardial Perfusion ImagingSensitivity and SpecificityTomography, Emission-Computed, Single-PhotonVectorcardiographyAdultAgedCoronary Artery DiseaseCoronary DiseaseFemaleHumansMaleMiddle AgedReproducibility of Results

Identifiers

PMID38378022
PMCPMC11136534

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.