Evidence map›Paper›PMID 38377518›Full record

ArticleJournal of child and adolescent psychopharmacology2024

Pharmacogenetic Factors Influence Escitalopram Pharmacokinetics and Adverse Events in Youth with a Family History of Bipolar Disorder: A Preliminary Study.

Duncan C Honeycutt, Thomas J Blom, Laura B Ramsey, Jeffrey R Strawn, Kaitlyn M Bruns, Jeffrey A Welge, Luis R Patino, Manpreet K Singh, Melissa P DelBello

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of child and adolescent psychopharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Duncan C HoneycuttDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.ORCID 0000-0001-9185-3321
Thomas J BlomDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Laura B RamseyDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.ORCID 0000-0001-6417-3961
Jeffrey R StrawnDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.ORCID 0000-0002-7526-2641
Kaitlyn M BrunsDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Jeffrey A WelgeDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Luis R PatinoDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.ORCID 0000-0002-1574-151X
Manpreet K SinghDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.
Melissa P DelBelloDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.ORCID 0000-0003-1837-4126
University of Cincinnati Medical Center · USChildren's Mercy Hospital · USCincinnati Children's Hospital Medical Center · USStanford University · US

Funding

2/2-Mechanism of Antidepressant-Related Dysfunctional Arousal in High-Risk YouthR01MH105469 · NIMH · STANFORD UNIVERSITY · PI SUPPES, TRISHA · 2015 to 2019
$2.6M
1/2-Mechanisms of Antidepressant-Related Dysfunctional Arousal in High-Risk YouthR01MH105464 · NIMH · UNIVERSITY OF CINCINNATI · PI DELBELLO, MELISSA P · 2015 to 2019
$2.6M
NIMH NIH HHS R01 MH105464NIMH NIH HHS R01 MH105469
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bipolar DisorderCitalopramAdolescentAntidepressive AgentsChildCytochrome P-450 CYP2C19Cytochrome P-450 CYP2D6EscitalopramGenotypeHumansPharmacogeneticsPsychomotor AgitationSerotonin Plasma Membrane Transport ProteinsAntidepressive AgentsCitalopramCytochrome P-450 CYP2C19Cytochrome P-450 CYP2D6EscitalopramSerotonin Plasma Membrane Transport ProteinsSLC6A4 protein, humanadolescentanxietybipolar disordersdepressionescitaloprampharmacogenetics

Identifiers

PMID38377518
PMCPMC10880264
OpenAlexW4391951896

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.