Evidence map›Paper›PMID 38377484›Full record

ArticleDiabetes care2024

Lifetime Duration of Breastfeeding and Cardiovascular Risk in Women With Type 2 Diabetes or a History of Gestational Diabetes: Findings From Two Large Prospective Cohorts.

Anna Birukov, Marta Guasch-Ferré, Sylvia H Ley, Deirdre K Tobias, Fenglei Wang, Clemens Wittenbecher, Jiaxi Yang, JoAnn E Manson, Jorge E Chavarro, Frank B Hu and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Implementation strategies: bridging obstetrics and long-term care.American journal of obstetrics & gynecology MFM · 2026
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  13. Sustained Reduction of Subclinical Inflammation in the Years After Breastfeeding.The Journal of clinical endocrinology and metabolism · 2025
    Article
  14. [Current Status and Advances in the Diagnosis and Management of Gestational Diabetes Mellitus: An Analysis of Relevant Contents in theSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 5 countries.

Anna BirukovDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.ORCID 0000-0002-8306-3351
Marta Guasch-FerréDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.ORCID 0000-0001-8525-1404
Sylvia H LeyDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA.ORCID 0000-0003-0084-2630
Deirdre K TobiasDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.ORCID 0000-0003-0020-9552
Fenglei WangDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.
Clemens WittenbecherDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.ORCID 0000-0001-7792-877X
Jiaxi YangGlobal Centre for Asian Women's Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID 0000-0002-4497-9615
JoAnn E MansonDivision of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Jorge E ChavarroDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.ORCID 0000-0002-4436-9630
Frank B HuDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.
Cuilin ZhangDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.ORCID 0000-0002-8014-2708
Brigham and Women's Hospital · USHarvard University · USNational University of Singapore · SGTulane University · USUniversity of Copenhagen · DK

Funding

Life Course Cancer Epidemiology Cohort in WomenU01CA176726 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 2018 to 2025
$22.4M
Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3M
Integrating lifecourse approaches, biologic and digital phenotypes in support of heart and lung disease epidemiologic researchU01HL145386 · NHLBI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI CHAVARRO, JORGE EDUARDO, MANSON, JOANN ELISABETH · 2019 to 2025
$17.8M
RISK FACTORS FOR CVD IN WOMENR01HL034594 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI JoAnn Elisabeth Manson, Lu Qi · 1985 to 2026
$13.8M
Risk Factors for Ischemic Stroke in WomenR01HL088521 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI REXRODE, KATHRYN M · 2008 to 2025
$9.9M
NCI NIH HHS U01 CA176726NCI NIH HHS UM1 CA186107NHLBI NIH HHS R01 HL034594NHLBI NIH HHS R01 HL088521NHLBI NIH HHS U01 HL145386NIH HHS U01 CA176726
6 · The paper itself

Abstract

objectiveBreastfeeding duration is inversely associated with risks of cardiovascular disease (CVD) and type 2 diabetes in parous women. However, the association among women at high risk, including women with type 2 diabetes or gestational diabetes mellitus (GDM) is unclear. RESEARCH DESIGN AND

methodsWe included 15,146 parous women with type 2 diabetes from the Nurses' Health Study I and II (NHS, NHS II) and 4,537 women with a history of GDM from NHS II. Participants reported history of breastfeeding via follow-up questionnaires. Incident CVD by 2017 comprised stroke or coronary heart disease (CHD) (myocardial infarction, coronary revascularization). Adjusted hazard ratios (aHRs) and 95% CIs were estimated using Cox models.

resultsWe documented 1,159 incident CVD cases among women with type 2 diabetes in both cohorts during 188,874 person-years of follow-up and 132 incident CVD cases among women with a GDM history during 100,218 person-years of follow-up. Longer lifetime duration of breastfeeding was significantly associated with lower CVD risk among women with type 2 diabetes, with pooled aHR of 0.68 (95% CI 0.54-0.85) for >18 months versus 0 months and 0.94 (0.91-0.98) per 6-month increment in breastfeeding. Similar associations were observed with CHD (pooled aHR 0.93 [0.88-0.97]) but not with stroke (0.96 [0.91-1.02]) per 6-month increment in breastfeeding. Among women with GDM history, >18 months versus 0 months of breastfeeding was associated with an aHR of 0.49 (0.28-0.86) for total CVD.

conclusionsLonger duration of breastfeeding was associated with lower risk of CVD in women with type 2 diabetes or GDM.

Indexed as

Cardiovascular DiseasesCoronary DiseaseDiabetes, GestationalDiabetes Mellitus, Type 2StrokeBreast FeedingFemaleHeart Disease Risk FactorsHumansPregnancyProspective StudiesRisk Factors

Identifiers

PMID38377484
PMCPMC11065777
OpenAlexW4391958317

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.