Evidence map›Paper›PMID 38377447›Full record

ReviewDiabetes2024

The Afferent Function of Adipose Innervation.

Yu Wang, Li Ye

Abstract readReview
In one paragraph

Review in Diabetes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yu WangDepartment of Neuroscience and Dorris Neuroscience Center, The Scripps Research Institute, La Jolla, CA.
Li YeDepartment of Neuroscience and Dorris Neuroscience Center, The Scripps Research Institute, La Jolla, CA.ORCID 0000-0002-3077-802X

Funding

The Role of Sensory Neurons Innervating Internal OrgansR01AT012051 · NCCIH · SCRIPPS RESEARCH INSTITUTE, THE · PI PATAPOUTIAN, ARDEM · 2022 to 2025
$2.9M
Modulating somatosensory network to target metabolic diseasesDP2DK128800 · NIDDK · SCRIPPS RESEARCH INSTITUTE, THE · PI YE, LI · 2020 to 2020
$2.7M
Brain-wide functional mapping of circuits controlling hedonic feeding in obesityK01DK114165 · NIDDK · STANFORD UNIVERSITY · PI YE, LI · 2017 to 2021
$825k
NCCIH NIH HHS R01 AT012051NCCIH NIH HHS R01AT012051NIDDK NIH HHS DP2 DK128800NIDDK NIH HHS DP2DK128800NIDDK NIH HHS K01 DK114165
6 · The paper itself

Abstract

Adipose tissue innervation is critical for regulating metabolic and energy homeostasis. While the sympathetic efferent innervation of fat is well characterized, the role of sensory or afferent innervation remains less explored. This article reviews previous work on adipose innervation and recent advances in the study of sensory innervation of adipose tissues. We discuss key open questions, including the physiological implications of adipose afferents in homeostasis as well as potential cross talk with sympathetic neurons, the immune system, and hormonal pathways. We also outline the general technical challenges of studying dorsal root ganglia innervating fat, along with emerging technologies that may overcome these barriers. Finally, we highlight areas for further research to deepen our understanding of the afferent function of adipose innervation.

Indexed as

Ganglia, SpinalNeurons, AfferentAdipose Tissue

Identifiers

PMID38377447
PMCPMC10882147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.