Evidence map›Paper›PMID 38377237›Full record

ReviewCirculation. Cardiovascular imaging2024

Machine Learning and Bias in Medical Imaging: Opportunities and Challenges.

Amey Vrudhula, Alan C Kwan, David Ouyang, Susan Cheng

Abstract readReview
In one paragraph

Review in Circulation. Cardiovascular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  13. Explainable AI: Ethical Frameworks, Bias, and the Necessity for Benchmarks.European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amey VrudhulaIcahn School of Medicine at Mount Sinai, New York (A.V.).ORCID 0000-0001-8895-1238
Alan C KwanDepartment of Cardiology, Smidt Heart Institute (A.V., A.C.K., D.O., S.C.), Cedars-Sinai Medical Center.ORCID 0000-0002-4393-1011
David Ouyang *Department of Cardiology, Smidt Heart Institute (A.V., A.C.K., D.O., S.C.), Cedars-Sinai Medical Center.ORCID 0000-0002-3813-7518
Susan Cheng *Department of Cardiology, Smidt Heart Institute (A.V., A.C.K., D.O., S.C.), Cedars-Sinai Medical Center.ORCID 0000-0002-4977-036X

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Cardiac microstructure and the immune-inflammatory response to SARS-CoV-2R01HL131532 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI CHENG, SUSAN, LI, DEBIAO · 2016 to 2025
$6.6M
Ventricular-vascular coupling in the elderly: lifecourse determinants, trajectories, and prognostic significanceR01HL142983 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHENG, SUSAN, MITCHELL, GARY FRANK · 2019 to 2022
$3.2M
Deep Learning Based Phenotyping and Outcomes Prediction for Valvular Heart DiseaseR01HL173526 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI David Ouyang · 2024 to 2026
$2.5M
Deep Learning Assessment of the Right Ventricle: Function, Etiology, and PrognosisR00HL157421 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI OUYANG, DAVID · 2023 to 2025
$747k
American Heart Association-American Stroke Association 23CDA1053659NCATS NIH HHS UL1 TR001881NHLBI NIH HHS R00 HL157421NHLBI NIH HHS R01 HL131532NHLBI NIH HHS R01 HL142983NHLBI NIH HHS R01 HL173526
6 · The paper itself

Abstract

Bias in health care has been well documented and results in disparate and worsened outcomes for at-risk groups. Medical imaging plays a critical role in facilitating patient diagnoses but involves multiple sources of bias including factors related to access to imaging modalities, acquisition of images, and assessment (ie, interpretation) of imaging data. Machine learning (ML) applied to diagnostic imaging has demonstrated the potential to improve the quality of imaging-based diagnosis and the precision of measuring imaging-based traits. Algorithms can leverage subtle information not visible to the human eye to detect underdiagnosed conditions or derive new disease phenotypes by linking imaging features with clinical outcomes, all while mitigating cognitive bias in interpretation. Importantly, however, the application of ML to diagnostic imaging has the potential to either reduce or propagate bias. Understanding the potential gain as well as the potential risks requires an understanding of how and what ML models learn. Common risks of propagating bias can arise from unbalanced training, suboptimal architecture design or selection, and uneven application of models. Notwithstanding these risks, ML may yet be applied to improve gain from imaging across all 3A's (access, acquisition, and assessment) for all patients. In this review, we present a framework for understanding the balance of opportunities and challenges for minimizing bias in medical imaging, how ML may improve current approaches to imaging, and what specific design considerations should be made as part of efforts to maximize the quality of health care for all.

Indexed as

AlgorithmsMachine LearningHumansartificial intelligencebiasdiagnostic imaginghealth equitymachine learning

Identifiers

PMID38377237
PMCPMC10883605

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.