Evidence map›Paper›PMID 38377210›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Instant tough adhesion of polymer networks.

Benjamin R Freedman, Juan A Cintron Cruz, Phoebe Kwon, Matthew Lee, Haley M Jeffers, Daniel Kent, Kyle C Wu, James C Weaver, David J Mooney

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

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  12. Soft elasticity enabled adhesion enhancement of liquid crystal elastomers on rough surfaces.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. Instant welding of gels by dry chitosan interlayers.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Instant tough adhesion of polymer networks.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Benjamin R Freedman *Department of Bioengineering, John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02139.
Juan A Cintron Cruz *Department of Bioengineering, John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02139.
Phoebe KwonWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215.
Matthew LeeDepartment of Bioengineering, John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02139.
Haley M JeffersDepartment of Bioengineering, John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02139.
Daniel KentWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215.ORCID 0009-0006-2464-2747
Kyle C WuDepartment of Orthopaedic Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215.ORCID 0000-0003-0009-5049
James C WeaverWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA 02215.
David J MooneyDepartment of Bioengineering, John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02139.ORCID 0000-0001-6299-1194
Harvard University · USBeth Israel Deaconess Medical Center · USBrigham and Women's Hospital · US

Funding

Supplement Multifunctional Tough Adhesive Hydrogels to Recruit, Expand, and Deliver Tendon Cells During Aging and InjuryR00AG065495 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Benjamin Ross Freedman · 2023 to 2026
$842k
Multifunctional tough adhesive hydrogels to recruit, expand, and deliver tendoncells during aging and injuryK99AG065495 · NIA · HARVARD UNIVERSITY · PI FREEDMAN, BENJAMIN ROSS · 2020 to 2022
$341k
NIA NIH HHS K99 AG065495NIA NIH HHS R00 AG065495NIH HHS K99AG065495NIH HHS R00AG065495
6 · The paper itself

Abstract

Generating strong rapid adhesion between hydrogels has the potential to advance the capabilities of modern medicine and surgery. Current hydrogel adhesion technologies rely primarily on liquid-based diffusion mechanisms and the formation of covalent bonds, requiring prolonged time to generate adhesion. Here, we present a simple and versatile strategy using dry chitosan polymer films to generate instant adhesion between hydrogel-hydrogel and hydrogel-elastomer surfaces. Using this approach we can achieve extremely high adhesive energies (>3,000 J/m

Indexed as

AdhesivesPolymersElastomersHumansHydrogelsTissue AdhesionsAdhesivesElastomersHydrogelsPolymersadhesivebioinspirationbiomaterialshydrogeltissue engineering

Identifiers

PMID38377210
PMCPMC10907230
OpenAlexW4391952899

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.