Evidence map›Paper›PMID 38376991›Full record

ArticleJournal of virology2024

Collateral sensitivity increases the efficacy of a rationally designed bacteriophage combination to control

Luke Acton, Hannah V Pye, Gaëtan Thilliez, Rafał Kolenda, Michaela Matthews, A Keith Turner, Muhammad Yasir, Emma Holden, Haider Al-Khanaq, Mark Webber and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Isolation of phages infecting the zoonotic pathogenbioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Luke ActonQuadram Institute Biosciences, Norwich Research Park, Norwich, United Kingdom.
Hannah V PyeQuadram Institute Biosciences, Norwich Research Park, Norwich, United Kingdom.
Gaëtan ThilliezQuadram Institute Biosciences, Norwich Research Park, Norwich, United Kingdom.
Rafał KolendaQuadram Institute Biosciences, Norwich Research Park, Norwich, United Kingdom.
Michaela MatthewsQuadram Institute Biosciences, Norwich Research Park, Norwich, United Kingdom.
A Keith TurnerQuadram Institute Biosciences, Norwich Research Park, Norwich, United Kingdom.
Muhammad YasirQuadram Institute Biosciences, Norwich Research Park, Norwich, United Kingdom.
Emma HoldenQuadram Institute Biosciences, Norwich Research Park, Norwich, United Kingdom.ORCID 0000-0002-0811-1675
Haider Al-KhanaqQuadram Institute Biosciences, Norwich Research Park, Norwich, United Kingdom.
Mark WebberQuadram Institute Biosciences, Norwich Research Park, Norwich, United Kingdom.ORCID 0000-0001-9169-7592
Evelien M AdriaenssensQuadram Institute Biosciences, Norwich Research Park, Norwich, United Kingdom.ORCID 0000-0003-4826-5406
Robert A KingsleyQuadram Institute Biosciences, Norwich Research Park, Norwich, United Kingdom.ORCID 0000-0002-0194-6485
Norwich Research Park · GBUniversity of East Anglia · GB

Funding

UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/M011216/1, BB/X011011/1, BB/R012504/1, BB/R506126/1
6 · The paper itself

Abstract

The ability of virulent bacteriophages to lyse bacteria influences bacterial evolution, fitness, and population structure. Knowledge of both host susceptibility and resistance factors is crucial for the successful application of bacteriophages as biological control agents in clinical therapy, food processing, and agriculture. In this study, we isolated 12 bacteriophages termed SPLA phage which infect the foodborne pathogen

Indexed as

BacteriophagesEnvironmental MicrobiologySalmonella entericaAnti-Bacterial AgentsDrug Collateral SensitivityHumansLipopolysaccharidesPhage TherapySalmonella InfectionsAnti-Bacterial AgentsLipopolysaccharidesantimicrobialBtuBcollateral sensitivityLPSphageTraDIS

Identifiers

PMID38376991
PMCPMC10949491
OpenAlexW4391972329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.