Evidence map›Paper›PMID 38376885›Full record

ArticleNeurobiology of aging2024

In vivo tau is associated with change in memory and processing speed, but not reasoning, in cognitively unimpaired older adults.

Sharon Sanz Simon, Eleanna Varangis, Seonjoo Lee, Yian Gu, Yunglin Gazes, Qolamreza R Razlighi, Christian Habeck, Yaakov Stern

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurobiology of aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sharon Sanz SimonCognitive Neuroscience Division, Department of Neurology, Columbia University, Vagelos College of Physicians and Surgeons, New York, NY, USA.
Eleanna VarangisSchool of Kinesiology, University of Michigan, Ann Arbor, MI, USA; Concussion Center, University of Michigan, Ann Arbor, MI, USA.
Seonjoo LeeDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA.
Yian GuCognitive Neuroscience Division, Department of Neurology, Columbia University, Vagelos College of Physicians and Surgeons, New York, NY, USA; Department of Epidemiology, Joseph P. Mailman School of Public Health, Columbia University, New York, NY, USA.
Yunglin GazesCognitive Neuroscience Division, Department of Neurology, Columbia University, Vagelos College of Physicians and Surgeons, New York, NY, USA.
Qolamreza R RazlighiDepartment of Radiology, Weill Cornell Medicine, New York City, NY, USA.
Christian HabeckCognitive Neuroscience Division, Department of Neurology, Columbia University, Vagelos College of Physicians and Surgeons, New York, NY, USA.
Yaakov SternCognitive Neuroscience Division, Department of Neurology, Columbia University, Vagelos College of Physicians and Surgeons, New York, NY, USA. Electronic address: ys11@columbia.edu.
Columbia University · USCornell University · USUniversity of Michigan–Ann Arbor · US

Funding

Exploring Cognitive Aging Using Reference Ability Neural NetworksR01AG038465 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HABECK, CHRISTIAN GEORG, STERN, YAAKOV · 2011 to 2025
$17.0M
Imaging of Cognition, Learning and Memory in AgingR01AG026158 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STERN, YAAKOV · 2004 to 2021
$10.9M
Exercise, aging, and cognition: Effect and mechanismsR01AG033546 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SLOAN, RICHARD P, STERN, YAAKOV · 2010 to 2014
$4.9M
Web-based technology and cognitive training: improving executive control in cognitivelyhealthy older adultsK99AG078561 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SANZ SIMON, SHARON · 2022 to 2023
$261k
NIA NIH HHS K99 AG078561NIA NIH HHS R01 AG026158NIA NIH HHS R01 AG033546NIA NIH HHS R01 AG038465
6 · The paper itself

Abstract

The relationship between tau deposition and cognitive decline in cognitively healthy older adults is still unclear. The tau PET tracer

Indexed as

Alzheimer DiseaseProcessing SpeedAgedAgingAmyloid beta-PeptidesHumansRetrospective StudiesAmyloid beta-PeptidesAgingAlzheimer’s diseaseMemoryPositron emission tomographySpeedTau

Identifiers

PMID38376885
PMCPMC10879688
OpenAlexW4387398480

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.