Evidence map›Paper›PMID 38376629›Full record

ArticleAnnals of nuclear medicine2024

A fully automatic deep learning-based method for segmenting regions of interest and predicting renal function in pediatric dynamic renal scintigraphy.

Xueli Ji, Guohui Zhu, Jinyu Gou, Suyun Chen, Wenyu Zhao, Zhanquan Sun, Hongliang Fu, Hui Wang

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Article in Annals of nuclear medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

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3 · Its place in the literature

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0 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xueli Ji *Department of Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Guohui Zhu *Institute of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai, 200092, China.
Jinyu Gou *Department of Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Suyun ChenDepartment of Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Wenyu ZhaoDepartment of Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.
Zhanquan SunInstitute of Optical-Electrical and Computer Engineering, University of Shanghai for Science and Technology, Shanghai, 200092, China. sunzhq@usst.edu.cn.
Hongliang FuDepartment of Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. fu_hongliang@163.com.
Hui WangDepartment of Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China. wanghui@xinhuamed.com.cn.ORCID http://orcid.org/0000-0001-5109-8691
Shanghai Jiao Tong University · CNUniversity of Shanghai for Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAccurate delineation of renal regions of interest (ROIs) is critical for the assessment of renal function in pediatric dynamic renal scintigraphy (DRS). The purpose of this study was to develop and evaluate a deep learning (DL) model that can fully automatically delineate renal ROIs and calculate renal function in pediatric

methodsThis study retrospectively analyzed 1,283 pediatric DRS data at a single center from January to December 2018. These patients were divided into training set (n = 1027), validation set (n = 128), and testing set (n = 128). A fully automatic segmentation of ROIs (FASR) model was developed and evaluated. The pixel values of the automatically segmented ROIs were calculated to predict renal blood perfusion rate (BPR) and differential renal function (DRF). Precision, recall rate, intersection over union (IOU), and Dice similarity coefficient (DSC) were used to evaluate the performance of FASR model. Intraclass correlation (ICC) and Pearson correlation analysis were used to compare the consistency of automatic and manual method in assessing the renal function parameters in the testing set.

resultsThe FASR model achieved a precision of 0.88, recall rate of 0.94, IOU of 0.83, and DSC of 0.91. In the testing set, the r values of BPR and DRF calculated by the two methods were 0.94 (P < 0.01) and 0.97 (P < 0.01), and the ICCs (95% confidence interval CI) were 0.94 (0.90-0.96) and 0.94 (0.91-0.96).

conclusionWe propose a reliable and stable DL model that can fully automatically segment ROIs and accurately predict renal function in pediatric

Indexed as

Deep LearningChildHumansKidneyKidney Function TestsRadionuclide ImagingRetrospective StudiesDeep learningDynamic renal scintigraphyPediatricRegions of interestRenal function

Identifiers

PMID38376629
OpenAlexW4391970023

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.