Evidence map›Paper›PMID 38376483›Full record

ArticleMolecules and cells2024

A comparison study of pathological features and drug efficacy between Drosophila models of C9orf72 ALS/FTD.

Davin Lee, Hae Chan Jeong, Seung Yeol Kim, Jin Yong Chung, Seok Hwan Cho, Kyoung Ah Kim, Jae Ho Cho, Byung Su Ko, In Jun Cha, Chang Geon Chung and 2 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules and cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Decoding Nucleotide Repeat Expansion Diseases: Novel Insights fromInternational journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Davin LeeDepartment of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Republic of Korea.
Hae Chan JeongDepartment of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Republic of Korea.
Seung Yeol KimSK Biopharmaceuticals Co., Ltd., Seongnam 13494, Republic of Korea.
Jin Yong ChungSK Biopharmaceuticals Co., Ltd., Seongnam 13494, Republic of Korea.
Seok Hwan ChoSK Biopharmaceuticals Co., Ltd., Seongnam 13494, Republic of Korea.
Kyoung Ah KimDepartment of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Republic of Korea.
Jae Ho ChoDepartment of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Republic of Korea.
Byung Su KoDepartment of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Republic of Korea.
In Jun ChaBrain Research Policy Center, Korea Brain Research Institute, Daegu 41068, Republic of Korea.
Chang Geon ChungDepartment of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Eun Seon KimDepartment of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Republic of Korea.
Sung Bae LeeDepartment of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Republic of Korea.
Daegu Gyeongbuk Institute of Science and Technology · KRHanall Biopharma (South Korea) · KRJohns Hopkins Medicine · USKorea Brain Research Institute · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyotrophic lateral sclerosis is a devastating neurodegenerative disease with a complex genetic basis, presenting both in familial and sporadic forms. The hexanucleotide (G

Indexed as

Amyotrophic Lateral SclerosisFrontotemporal DementiaNeurodegenerative DiseasesAnimalsC9orf72 ProteinDrosophilaLevamisole3-aminolevamisoleC9orf72 ProteinLevamisoleAmyotrophic lateral sclerosisC9orf72Comparison studyDrug screeningG(4)C(2) repeat expansion models

Identifiers

PMID38376483
PMCPMC10880080
OpenAlexW4390081147

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.