ReviewRenal failure2023
Wasp venom-induced acute kidney injury: current progress and prospects.
Review in Renal failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Snake envenomation and acute kidney injury: a systematic review and meta-analysis.BMC nephrology · 2026Pooled it
- Development and validation of an early prediction model for bee-sting-induced acute kidney injury using machine learning.Renal failure · 2026Article
- The predictive value of early systemic inflammatory response index (SIRI), serum βRenal failure · 2026Article
- Transcriptome-Metabolome Integration Deciphers the Metabolic and Transcriptional Reprogramming in Mice Due toToxins · 2026Article
- From Sting to Strain: A Case Report of Wasp Sting-Induced Multiorgan Dysfunction Syndrome.Cureus · 2026Article
- Clinical characteristics of older people and risk factors for developing multiple organ dysfunction following wasp stings.European geriatric medicine · 2026Article
- Early Plasma Exchange for Multiple Organ Failure Following Massive Wasp Stings: A Case Report.Cureus · 2026Article
- Acute Neurological and Respiratory Complications Induced by Wasp Stings: A Case Report.The American journal of case reports · 2026Article
- Emergency response and clinical treatment analysis of a mass wasp sting incident involving 38 tourists: A case report.Medicine · 2026Article
- Complement in acute kidney injury: a convergent pathogenic pathway in multifactorial renal damage.Frontiers in immunology · 2026Review
- From sting to STING: role of inflammation in wasp sting induced AKI - a narrative review.BMC nephrology · 2025Review
- Multisystem injury after wasp stings in the Qinling range, Shaanxi, China: clinical profile and independent predictors of poor outcome.Frontiers in medicine · 2025Article
- Risk Prediction of Severe Complications Caused by Hymenoptera Insect Stings: Development and Validation of a Nomogram Mode.Journal of inflammation research · 2025Article
- The role of mitochondrial reactive oxygen species in initiating mitochondrial damage and inflammation in wasp-venom-induced acute kidney injury.Journal of toxicologic pathology · 2025Article
- Case Report: Multi organ dysfunction in a dog following massive paper wasp (Frontiers in veterinary science · 2025Article
- Complement activation in wasp venom-induced acute kidney injury.Renal failure · 2024Article
- A rare concurrence of acute tubular necrosis and chronic glomerular sclerosis in a patient with wasp stings.Heliyon · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wasp venom can trigger local and systemic reactions, with the kidneys being commonly affected, potentially causing acute kidney injury (AKI). Despite of the recent advances, our knowledge on the underlying mechanisms of toxicity and targeted therapies remain poor. AKI can result from direct nephrotoxic effects of the wasp venom or secondary rhabdomyolysis and intravascular hemolysis, which will release myoglobin and free hemoglobin. Inflammatory responses play a central role in these pathological mechanisms. Noteworthily, the successful establishment of a suitable experimental model can assist in basic research and clinical advancements related to wasp venom-induced AKI. The combination of therapeutic plasma exchange and continuous renal replacement therapy appears to be the preferred treatment for wasp venom-induced AKI. In addition, studies on cilastatin and varespladib for wasp venom-induced AKI treatment have shown their potential as therapeutic agents. This review summarizes the available evidence on the mechanisms and treatment of wasp venom-induced AKI, with a particular focus on the role of inflammatory responses and potential targets for therapeutic drugs, and, therefore, aiming to support the development of clinical treatment against wasp venom-induced AKI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.