Evidence map›Paper›PMID 38375059›Full record

ArticleJACC. Advances2024

The Science of Precision Prevention: Research Opportunities and Clinical Applications to Reduce Cardiovascular Health Disparities.

Thomas A Pearson, Debbie Vitalis, Charlotte Pratt, Rebecca Campo, Antonis A Armoundas, David Au, Bettina Beech, Olga Brazhnik, Christopher G Chute, Karina W Davidson and 18 more

Abstract read
In one paragraph

Article in JACC. Advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Thomas A PearsonCollege of Medicine and College of Public Health and Health Professions, University of Florida Health Science Center, Gainesville, Florida, USA.
Debbie VitalisDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Charlotte PrattDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Rebecca CampoDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Antonis A ArmoundasCardiovascular Research Center, Massachusetts General Hospital and Broad Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
David AuCenter of Innovation for Veteran-Centered and Value-Driven Care, University of Washington, Seattle, Washington, USA.
Bettina BeechUH Population Health, University of Houston, Houston, Texas, USA.
Olga BrazhnikDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Christopher G ChuteJohns Hopkins Medicine, Institute for Clinical and Translational Research, Baltimore, Maryland, USA.
Karina W DavidsonInstitute of Health System Science, Feinstein Institutes for Medical Research, Northwell Health, New Hyde Park, New York, USA.
Ana V Diez-RouxUrban Health Collaborative, Drexel Dornsife School of Public Health, Philadelphia, Pennsylvania, USA.
Lawrence J FineDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Davera GabrielBiomedical Informatics and Data Science Section, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Peter GroenveldCenter for Health Care Transformation and Innovation, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Jaclyn HallDepartment of Health Outcomes and Biomedical Informatics, Institute for Child Health Policy, College of Medicine, University of Florida, Gainesville, Florida, USA.
Alison B HamiltonCenter for the Study of Healthcare Innovation, Implementation & Policy, VA Greater Los Angeles Healthcare System, Los Angeles, California, USA.
Hui HuChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Heng JiDepartment of Computer Science, University of Illinois Urbana-Champaign, Champaign, Illinois, USA.
Amy KindCenter for Health Disparities Research (CHDR), University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
William E KrausDuke Molecular Physiology Institute, School of Medicine, Duke University, Durham, North Carolina, USA.
Harlan KrumholzInstitute for Social and Policy Studies, of Investigative Medicine and of Public Health (Health Policy), Yale University, New Haven, Connecticut, USA.
George A MensahCenter for Translation Research and Implementation Science, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Raina M MerchantCenter for Health Care Transformation and Innovation, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Dariush MozaffarianFriedman School of Nutrition Science & Policy, Tufts University, Medford, Massachusetts, USA.
David M MurrayOffice of Disease Prevention, National Institutes of Health, Bethesda, Maryland, USA.
Dianne Neumark-SztainerDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.
Maya PetersenDivision of Biostatistics, and UCSF-UC Berkeley Program in Computational Precision Health, School of Public Health, University of California-Berkeley, Berkeley, California, USA.
David GoffDivision of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Digital Phenotyping and Cardiovascular HealthR01HL141844 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MERCHANT, RAINA · 2019 to 2022
$3.1M
Hypertensive Disorders of Pregnancy and Early Risk of Maternal CVD: Influence of the External ExposomeK01HL153797 · NHLBI · UNIVERSITY OF FLORIDA · PI HU, HUI · 2021 to 2025
$874k
Intramural NIH HHS Z99 OD999999NCATS NIH HHS UL1 TR001863NHLBI NIH HHS K01 HL153797NHLBI NIH HHS R01 HL141844
6 · The paper itself

Abstract

Precision prevention embraces personalized prevention but includes broader factors such as social determinants of health to improve cardiovascular health. The quality, quantity, precision, and diversity of data relatable to individuals and communities continue to expand. New analytical methods can be applied to these data to create tools to attribute risk, which may allow a better understanding of cardiovascular health disparities. Interventions using these analytic tools should be evaluated to establish feasibility and efficacy for addressing cardiovascular disease disparities in diverse individuals and communities. Training in these approaches is important to create the next generation of scientists and practitioners in precision prevention. This state-of-the-art review is based on a workshop convened to identify current gaps in knowledge and methods used in precision prevention intervention research, discuss opportunities to expand trials of implementation science to close the health equity gaps, and expand the education and training of a diverse precision prevention workforce.

Indexed as

data sciencehealth equityhealth promotionimplementation sciencepersonalized medicineprecision analytics

Identifiers

PMID38375059
PMCPMC10876066

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.