Jatonik polyherbal mixture induced rat liver MMPT pore opening in normal Wistar rat:

Olabinri P Folashade, Ibrahim Damilare Boyenle, Tolulope A Oyedeji, Fiyinfoluwa Demilade Ojeniyi, Adisa Ayobami Damilare, Leonard O Ehigie, Adeola Folasade Ehigie

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In one paragraph

Article in Chinese herbal medicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Olabinri P FolashadeMembrane Biochemistry and Biophysics Research Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso 210214, Nigeria.

Ibrahim Damilare BoyenleMembrane Biochemistry and Biophysics Research Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso 210214, Nigeria.

Tolulope A OyedejiDepartment of Biochemistry, University of Lagos, Lagos 101017, Nigeria.

Fiyinfoluwa Demilade OjeniyiComputational Biology/Drug Discovery Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso 210214, Nigeria.

Adisa Ayobami DamilareMembrane Biochemistry and Biophysics Research Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso 210214, Nigeria.

Leonard O EhigieComputational Biology/Drug Discovery Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso 210214, Nigeria.

Adeola Folasade EhigieMembrane Biochemistry and Biophysics Research Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso 210214, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess acute toxicity, the Methods: Acute toxicity of JME and JEE was determined using Lorke's method. Results: JME had an LD Conclusion: Jatonik extracts may be a promising target for drug development in diseases where there is dysregulation of apoptosis, however, further studies are needed to better clarify the molecular mechanism involved in these phenomena.

Indexed as

acute toxicityAgeratum conyzoides Linn.apoptosisHunteria umbellate (K. Schum.) Hallier f.Lepidium meyenii Walp.mitochondrial ATPasemitochondrial lipid peroxidationmitochondrial membrane permeability transition porepolyherbal mixtureXylopia aethiopica (Dunal) A. Rich

Identifiers

PMID38375053

DOI10.1016/j.chmed.2023.06.002

PMCPMC10874763

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.