Evidence map›Paper›PMID 38374913›Full record

SynthesisVascular health and risk management2024

Arterial Stiffness and Aortic Aneurysmal Disease - A Narrative Review.

Konstantinos G Moulakakis, Christos F Pitros, Ioannis T Theodosopoulos, Spyridon N Mylonas, John D Kakisis, Christos Manopoulos, Nikolaos P E Kadoglou

Abstract readSystematic Review
In one paragraph

Synthesis in Vascular health and risk management, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Observational
  2. Article
  3. Sac Shrinkage after Endovascular Aneurysm Repair: New Insights into Aneurysm Wall Degeneration and Loss of Elasticity.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Konstantinos G Moulakakis *Department of Vascular Surgery, Patras University Hospital, University of Patras, Patras, Greece.ORCID 0000-0002-2269-5937
Christos F Pitros *Department of Vascular Surgery, Patras University Hospital, University of Patras, Patras, Greece.ORCID 0000-0002-2453-2664
Ioannis T TheodosopoulosDepartment of Vascular Surgery, "Attikon" University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Spyridon N MylonasDepartment of Vascular and Endovascular Surgery, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, 50937, Germany.ORCID 0000-0002-9875-4614
John D KakisisDepartment of Vascular Surgery, "Attikon" University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Christos ManopoulosBiofluid Mechanics and Biomedical Engineering Laboratory, Fluids Section, School of Mechanical Engineering, National Technical University of Athens, Athens, Greece.
Nikolaos P E KadoglouMedical School, University of Cyprus, Nicosia, Cyprus.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been documented that large-artery stiffness is independently associated with increased cardiovascular risk and may potentially lead to heart and kidney failure and cerebrovascular disease. A systematic review of studies investigating changes in arterial stiffness in patients undergoing endovascular repair of aortic disease was conducted. In addition, a review of the available literature was performed, analyzing findings from studies using the cardio-ankle vascular index (CAVI) as a marker of arterial stiffness. Overall, 26 studies were included in the present analysis. Our research revealed a high heterogeneity of included studies regarding the techniques used to assess the aortic stiffness. Aortic stiffness was assessed by pulse wave velocity (PWV), elastic modulus (Ep), and augmentation index (AI). Currently a few studies exist investigating the role of CAVI in patients having an aortic aneurysm or undergoing endovascular aortic repair. The majority of studies showed that the treatment of an abdominal aortic aneurysm (AAA) either with open repair (OR) or endovascular aortic repair (EVAR) reduces aortic compliance significantly. Whether EVAR reconstruction might contribute a higher effect on arterial stiffness compared to OR needs further focused research. An increase of arterial stiffness was uniformly observed in studies investigating patients following thoracic endovascular aortic repair (TEVAR), and the effect was more pronounced in young patients. The effects of increased arterial stiffness after EVAR and TEVAR on the heart and the central hemodynamic, and an eventual effect on cardiac systolic function, need to be further investigated and evaluated in large studies and special groups of patients.

Indexed as

Aortic Aneurysm, AbdominalEndovascular ProceduresPulse Wave AnalysisVascular StiffnessAdultAgedAged, 80 and overAortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationCardio Ankle Vascular IndexFemaleHemodynamicsHumansMaleMiddle AgedPredictive Value of TestsAIaortic aneurysmarterial stiffnessaugmentation indexcardio-ankle vascular indexCAVIendovascular aortic aneurysm repairEVARpulse wave velocityPWVTEVARthoracic endovascular aortic aneurysm repair

Identifiers

PMID38374913
PMCPMC10875171

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.