Evidence map›Paper›PMID 38374866›Full record

ArticleCureus2024

A Rare Coexistence of Smoldering Multiple Myeloma and JAK2-Positive Myeloproliferative Neoplasm: A Case of Dual Synchronous Hematological Malignancy.

Adnane Hammani, Othman Doghmi, Mohammed Allaoui, Mounir Ababou, El Mehdi Mahtat, Hicham El Maaroufi, Kamal Doghmi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adnane HammaniHematology, Mohammed V Military Training Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.
Othman DoghmiHematology, Ibn Sina University Hospital Center, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.
Mohammed AllaouiPathology, Mohammed V Military Training Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.
Mounir AbabouHematology, Mohammed V Military Training Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.
El Mehdi MahtatHematology, Mohammed V Military Training Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.
Hicham El MaaroufiHematology, Mohammed V Military Training Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.
Kamal DoghmiHematology, Mohammed V Military Training Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article explores the rare case of an 82-year-old man diagnosed concurrently with essential thrombocythemia and smoldering multiple myeloma (SMM). The limited existing literature on individuals harboring both myeloproliferative neoplasm (MPN) and monoclonal gammopathy (MG) is of significant interest due to the distinct origins of these malignancies. The etiology of MG in MPN patients remains elusive, leading to speculation about a potential relationship or interplay between the two conditions. This unique case prompts a deeper exploration of the mechanisms underlying the coexistence of JAK2-positive MPN and SMM. It underscores the importance of tailored therapeutic strategies that carefully consider the inherent risks and potential adverse outcomes associated with these specific malignancies, thereby warranting further clinical research.

Indexed as

essential thrombocythemiajak2 mutationmonoclonal gammopathymyeloproliferative neoplasmsmoldering multiple myelomasynchronous dual hematological malignancy

Identifiers

PMID38374866
PMCPMC10876019

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.