Evidence map›Paper›PMID 38374529›Full record

ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2024

Is extended venous thromboprophylaxis required in patients undergoing ileal pouch procedure for ulcerative colitis?

Javier Gomez, Evangelia Theodosopoulos, Helen MacRae, Mantaj S Brar, Anthony de Buck van Overstraeten, Brenda O'Connor, Harden Huang, Erin Kennedy

Abstract read
In one paragraph

Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Is extended venous thromboprophylaxis required in patients undergoing ileal pouch procedure for ulcerative colitis?Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Javier GomezDepartment of Surgery, University of Toronto, Toronto, Ontario, Canada.
Evangelia TheodosopoulosDepartment of Surgery, University of Toronto, Toronto, Ontario, Canada.
Helen MacRaeDepartment of Surgery, University of Toronto, Toronto, Ontario, Canada.
Mantaj S BrarDepartment of Surgery, University of Toronto, Toronto, Ontario, Canada.
Anthony de Buck van OverstraetenDepartment of Surgery, University of Toronto, Toronto, Ontario, Canada.
Brenda O'ConnorZane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada.
Harden HuangZane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada.
Erin KennedyDepartment of Surgery, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-0707-5294

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimVenous thromboembolic events (VTEs) are relatively common adverse surgical complications. Extended VTE prophylaxis for 4 weeks is recommended after colorectal cancer surgery, but its use in inflammatory bowel disease surgery lacks high-quality evidence. This retrospective study aimed to assess and characterize VTEs within the first 30 days after ileal pouch-anal anastomosis (IPAA) procedures and subtotal colectomies (STCs) for ulcerative colitis (UC).

methodsAll patients who underwent IPAA for UC between 1 January 2017 and 31 December 2021 were included. VTE rates after IPAA, in-hospital or at-home occurrences, utilization of in-hospital thromboprophylaxis, and prescribed anticoagulant treatment were evaluated. Retrospectively, the same variables were analysed if patients of the cohort underwent STC before the IPAA construction.

resultsIn all, 204 patients underwent IPAA (61.8% men, 73% laparoscopic), with an average hospital stay of 6.8 days. Among them, 116 patients underwent STC prior to IPAA. Thirteen patients (6.3%) experienced VTEs after IPAA, with 76.9% (10/13) of cases occurring during hospitalization and under adequate thromboprophylaxis. The VTE rate after STC was 10.3% (12/116), with 58.2% (7/12) occurring in hospital and under appropriate thromboprophylaxis. No reoperations or mortality were attributed to thrombotic events. The type and duration of anticoagulant treatment varied considerably.

conclusionThe VTE rate after IPAA for UC was 6.3%, with the majority of events occurring in hospital and under adequate thromboprophylaxis. These findings suggest that routine use of extended VTE prophylaxis in our cohort may not be supported. Further research is needed to clarify the optimal VTE prophylaxis strategy for inflammatory bowel disease surgery.

Indexed as

AnticoagulantsColitis, UlcerativePostoperative ComplicationsProctocolectomy, RestorativeVenous ThromboembolismAdultColectomyFemaleHumansLength of StayMaleMiddle AgedRetrospective StudiesAnticoagulantsinflammatory bowel diseasesurgeryvenous thromboembolism

Identifiers

PMID38374529
PMCPMC12150822

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.