ArticleEuropean radiology2024
A modified CEUS risk stratification model for adnexal masses with solid components: prospective multicenter study and risk adjustment.
Article in European radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic value of contrast-enhanced ultrasound for the depth of myometrial infiltration in early endometrial cancer: a meta-analysis.Frontiers in oncology · 2025Pooled it
- The Quantification Paradox in Gynecologic Color Doppler Ultrasound: From Spectral Indices to Microvascular Imaging and Artificial Intelligence.International journal of women's health · 2026Review
- Contrast-enhanced ultrasound and Ovarian-Adnexal Reporting and Data System ultrasound classification for risk assessment of ovarian and adnexal lesions: a systematic review and meta-analysis.Quantitative imaging in medicine and surgery · 2026Article
- Contrast-enhanced ultrasound findings of ovarian Sertoli-Leydig cell tumor: a case report with ultrasonographic-pathological insights.BMC women's health · 2025Article
- Diagnostic value of contrast-enhanced ultrasound in endometrial lesions.BMC women's health · 2025Article
- Findings on conventional ultrasonography and contrast-enhanced ultrasonography in different histopathological subtypes of ovarian thecoma-fibroma group.BMC medical imaging · 2025Article
- Exploratory study on the enhancement of O-RADS application effectiveness for novice ultrasonographers via deep learning.Archives of gynecology and obstetrics · 2024Article
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Authors and funding
17 authors.
Funding
Abstract
objectivesTo evaluate the additional advantages of integrating contrast-enhanced ultrasound (CEUS) into the Ovarian-Adnexal Reporting and Data System (O-RADS) ultrasound (US) for the characterization of adnexal lesions with solid components. MATERIALS AND
methodsThis prospective multicenter study recruited women suspected of having adnexal lesions with solid components between September 2021 and December 2022. All patients scheduled for surgery underwent preoperative CEUS and US examinations. The lesions were categorized according to the O-RADS US system, and quantitative CEUS indexes were recorded. Pathological results served as the reference standard. Univariable and multivariable analyses were performed to identify risk factors for malignancy in adnexal lesions with solid components. Receiver operating characteristic (ROC) curve analysis was employed to assess diagnostic performance.
resultsA total of 180 lesions in 175 women were included in the study. Among these masses, 80 were malignant and 100 were benign. Multivariable analysis revealed that serum CA-125, the presence of acoustic shadowing, and peak intensity (PI) ratio (PI
conclusionOur findings underscore the potential value of CEUS as an adjunctive tool for enhancing the precision of diagnostic evaluations of O-RADS US. CLINICAL RELEVANCE STATEMENT: The promising performance of the modified CEUS risk stratification model suggests its potential to mitigate unnecessary surgeries in the characterization of adnexal lesions with solid components. KEY POINTS: • The additional value of CEUS to O-RADS US in distinguishing between benign and malignant adnexal lesions with solid components requires further evaluation. • The modified CEUS risk stratification model displayed superior diagnostic value and specificity in characterizing adnexal lesions with solid components when compared to O-RADS US. • The inclusion of CEUS demonstrated potential in reducing the need for unnecessary surgeries in the characterization of adnexal lesions with solid components.
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