Evidence map›Paper›PMID 38374297›Full record

ReviewInterdisciplinary sciences, computational life sciences2024

A Review of the Application of Spatial Transcriptomics in Neuroscience.

Le Zhang, Zhenqi Xiong, Ming Xiao

Abstract readReview
PubMed Publisher
In one paragraph

Review in Interdisciplinary sciences, computational life sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Le Zhang *College of Computer Science, Sichuan University, Chengdu, 610065, China.
Zhenqi Xiong *College of Computer Science, Sichuan University, Chengdu, 610065, China.
Ming XiaoCollege of Computer Science, Sichuan University, Chengdu, 610065, China. xiaoming@scu.edu.cn.ORCID http://orcid.org/0000-0001-8608-5903

Funding

China Postdoctoral Science Foundation 2020M673221Chongqing Technology Innovation and Application Development Project CSTB2022TIAD-KPX0067Fundamental Research Funds for the Central Universities 2020SCU12056National Natural Science Foundation of China 62372316National Science and Technology Major Project 2018ZX10201002National Science and Technology Major Project 2021YFF1201200Sichuan Science and Technology Program 2022YFS0048
6 · The paper itself

Abstract

Since spatial transcriptomics can locate and distinguish the gene expression of functional genes in special regions and tissue, it is important for us to investigate the brain development, the development mechanism of brain diseases, and the relationship between brain structure and function in Neuroscience (or Brain science). While previous studies have introduced the crucial spatial transcriptomic techniques and data analysis methods, there are few studies to comprehensively overview the key methods, data resources, and technological applications of spatial transcriptomics in Neuroscience. For these reasons, we first investigate several common spatial transcriptomic data analysis approaches and data resources. Second, we introduce the applications of the spatial transcriptomic data analysis approaches in Neuroscience. Third, we summarize the integrating spatial transcriptomics with other technologies in Neuroscience. Finally, we discuss the challenges and future research directions of spatial transcriptomics in Neuroscience.

Indexed as

NeurosciencesTranscriptomeAnimalsBrainComputational BiologyGene Expression ProfilingHumansMulti-omicsNeurosciencescRNA-seqSpatial transcriptomic techniques

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.