Evidence map›Paper›PMID 38374256›Full record

ArticleNature2024

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.

Ken Suzuki, Konstantinos Hatzikotoulas, Lorraine Southam, Henry J Taylor, Xianyong Yin, Kim M Lorenz, Ravi Mandla, Alicia Huerta-Chagoya, Giorgio E M Melloni, Stavroula Kanoni and 354 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 421 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
421citing papers in PubMed, 4 pooled it
243.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

421 citing papers in PubMed, 4 syntheses or guidelines pooled it, 445 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
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  10. Observational
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  20. Review

361 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

364 authors at 20 institutions in 32 countries.

Ken Suzuki *Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester, UK.
Konstantinos Hatzikotoulas *Institute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany. konstantinos.hatzikotoulas@helmholtz-munich.de.ORCID http://orcid.org/0000-0002-4699-3672
Lorraine Southam *Institute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Henry J Taylor *Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-2088-5240
Xianyong Yin *Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, China.ORCID http://orcid.org/0000-0001-6454-2384
Kim M Lorenz *Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0001-8674-2942
Ravi Mandla *Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Alicia Huerta-ChagoyaPrograms in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Giorgio E M MelloniTIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Stavroula KanoniWilliam Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Nigel W RaynerInstitute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Ozvan BocherInstitute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Ana Luiza ArrudaInstitute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Kyuto SoneharaDepartment of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
Shinichi NambaDepartment of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
Simon S K LeeCharles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Michael H PreussCharles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Lauren E PettyDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Philip SchroederPrograms in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Brett VanderwerffDepartment of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
Mart KalsEstonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Fiona BraggNuffield Department of Population Health, University of Oxford, Oxford, UK.
Kuang LinNuffield Department of Population Health, University of Oxford, Oxford, UK.
Xiuqing GuoInstitute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Weihua ZhangDepartment of Epidemiology and Biostatistics, Imperial College London, London, UK.
Jie YaoInstitute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Young Jin KimDivision of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, South Korea.
Mariaelisa GraffDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Fumihiko TakeuchiDepartment of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Jana NanoInstitute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Amel LamriDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Masahiro NakatochiPublic Health Informatics Unit, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Sanghoon MoonDivision of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, South Korea.
Robert A ScottMRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.
James P CookDepartment of Health Data Science, University of Liverpool, Liverpool, UK.
Jung-Jin LeeDivision of Translational Medicine and Human Genetics, University of Pennsylvania, Philadelphia, PA, USA.
Ian PanDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA.
Daniel TaliunDepartment of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
Esteban J ParraDepartment of Anthropology, University of Toronto at Mississauga, Mississauga, Ontario, Canada.
Jin-Fang ChaiSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Lawrence F BielakDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Yasuharu TabaraCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yang HaiInstitute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Gudmar ThorleifssondeCODE Genetics, Amgen, Reykjavik, Iceland.
Niels GrarupNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Tamar SoferDepartment of Biostatistics, Harvard University, Boston, MA, USA.
Matthias WuttkeInstitute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Chloé SarnowskiDepartment of Epidemiology, Human Genetics and Environmental Sciences, University of Texas Health Science Center at Houston School of Public Health, Houston, TX, USA.
Christian GiegerInstitute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Darryl NousomeDepartment of Population and Public Health Sciences, Keck School of Medicine of USC, Los Angeles, CA, USA.
Stella TrompetDepartment of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
Soo-Heon KwakDepartment of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.
Jirong LongDivision of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Meng SunNuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
Lin TongInstitute for Population and Precision Health (IPPH), Biological Sciences Division, University of Chicago, Chicago, IL, USA.
Wei-Min ChenDepartment of Public Health Sciences and Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA.
Suraj S NongmaithemGenomic Research on Complex Diseases (GRC-Group), CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad, India.
Raymond NoordamSection of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Victor J Y LimSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Claudia H T TamDepartment of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China.
Yoonjung Yoonie JooSamsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, Samsung Medical Center, Seoul, South Korea.
Chien-Hsiun ChenInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Laura M RaffieldDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Bram Peter PrinsDepartment of Human Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.
Aude NicolasLaboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Lisa R YanekDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Guanjie ChenCenter for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Jennifer A BrodyCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
Edmond KabagambeDivision of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Ping AnDivision of Statistical Genomics, Washington University School of Medicine, St Louis, MO, USA.
Anny H XiangDepartment of Research and Evaluation, Division of Biostatistics Research, Kaiser Permanente of Southern California, Pasadena, CA, USA.
Hyeok Sun ChoiDepartment of Biomedical Science, Hallym University, Chuncheon, South Korea.
Brian E CadeDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.
Jingyi TanInstitute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
K Alaine BroadawayDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Alice WilliamsonMRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Zoha KamaliDepartment of Epidemiology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
Jinrui CuiDepartment of Medicine, Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Manonanthini ThangamLund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden.
Linda S AdairDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Adebowale AdeyemoCenter for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Carlos A Aguilar-SalinasUnidad de Investigación en Enfermedades Metabólicas and Departamento de Endocrinología y Metabolismo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Tarunveer S AhluwaliaSteno Diabetes Center Copenhagen, Herlev, Denmark.
Sonia S AnandDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Alain BertoniDepartment of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Jette Bork-JensenNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Ivan BrandslundInstitute of Regional Health Research, University of Southern Denmark, Odense, Denmark.
Thomas A BuchananDepartment of Medicine, Division of Endocrinology and Diabetes, Keck School of Medicine of USC, Los Angeles, CA, USA.
Charles F BurantDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Adam S ButterworthBritish Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Mickaël CanouilInserm U1283, CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, Lille University Hospital, Lille, France.
Juliana C N ChanDepartment of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China.
Li-Ching ChangInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Miao-Li CheeSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Ji ChenExeter Centre of Excellence in Diabetes (ExCEeD), Exeter Medical School, University of Exeter, Exeter, UK.
Shyh-Huei ChenDepartment of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Yuan-Tsong ChenInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Zhengming ChenNuffield Department of Population Health, University of Oxford, Oxford, UK.
Lee-Ming ChuangDivision of Endocrinology and Metabolism, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Mary CushmanDepartment of Medicine, University of Vermont, Colchester, VT, USA.
John DaneshBritish Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Swapan K DasSection of Endocrinology and Metabolism, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.
H Janaka de SilvaDepartment of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
George DedoussisDepartment of Nutrition and Dietetics, Harokopio University of Athens, Athens, Greece.
Latchezar DimitrovCenter for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Ayo P DoumateyCenter for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Shufa DuDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Qing DuanDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kai-Uwe EckardtDepartment of Nephrology and Medical Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Leslie S EmeryDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
Daniel S EvansCalifornia Pacific Medical Center Research Institute, San Francisco, CA, USA.
Michele K EvansLaboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Krista FischerEstonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
James S FloydCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
Ian FordRobertson Centre for Biostatistics, University of Glasgow, Glasgow, UK.
Oscar H FrancoDepartment of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Timothy M FraylingGenetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK.
Barry I FreedmanDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Pauline GenterDepartment of Medicine, Division of Endocrinology and Metabolism, Lundquist Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.
Hertzel C GersteinDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Vilmantas GiedraitisDepartment of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
Clicerio González-VillalpandoCentro de Estudios en Diabetes, Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Publica, Mexico City, Mexico.
Maria Elena González-VillalpandoCentro de Estudios en Diabetes, Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Publica, Mexico City, Mexico.
Penny Gordon-LarsenDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Myron GrossDepartment of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.
Lindsay A GuareGenomics and Computational Biology Graduate Group, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Sophie HackingerDepartment of Human Genetics, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.
Liisa HakasteInstitute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
Sohee HanDivision of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, South Korea.
Andrew T HattersleyUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Christian HerderGerman Center for Diabetes Research (DZD), Neuherberg, Germany.
Momoko HorikoshiLaboratory for Genomics of Diabetes and Metabolism, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Annie-Green HowardCarolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Willa HsuehDepartment of Internal Medicine, Diabetes and Metabolism Research Center, Ohio State University Wexner Medical Center, Columbus, OH, USA.
Mengna HuangDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA.
Wei HuangShanghai-MOST Key Laboratory of Health and Disease Genomics, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, China.
Yi-Jen HungDivision of Endocrine and Metabolism, Tri-Service General Hospital Songshan Branch, Taipei, Taiwan.
Mi Yeong HwangDivision of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, Korea.
Chii-Min HwuSection of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Sahoko IchiharaDepartment of Environmental and Preventive Medicine, Jichi Medical University School of Medicine, Shimotsuke, Japan.
Mohammad Arfan IkramDepartment of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Martin IngelssonDepartment of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
Md Tariqul IslamUniversity of Chicago Research Bangladesh, Dhaka, Bangladesh.
Masato IsonoDepartment of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Hye-Mi JangDivision of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, Korea.
Farzana JasmineInstitute for Population and Precision Health (IPPH), Biological Sciences Division, University of Chicago, Chicago, IL, USA.
Guozhi JiangDepartment of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China.
Jost B JonasInstitute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland.
Torben JørgensenCenter for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Frederick K KamanuTIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Fouad R KandeelDepartment of Clinical Diabetes, Endocrinology and Metabolism, Department of Translational Research and Cellular Therapeutics, City of Hope, Duarte, CA, USA.
Anuradhani KasturiratneDepartment of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Tomohiro KatsuyaDepartment of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Osaka, Japan.
Varinderpal KaurDiabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Takahisa KawaguchiCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Jacob M KeatonCenter for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Abel N KhoDivision of General Internal Medicine and Geriatrics, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Chiea-Chuen KhorGenome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.
Muhammad G KibriyaInstitute for Population and Precision Health (IPPH), Biological Sciences Division, University of Chicago, Chicago, IL, USA.
Duk-Hwan KimDepartment of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, South Korea.
Florian KronenbergInstitute of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria.
Johanna KuusistoInstitute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Kristi LällEstonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Leslie A LangeDepartment of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.
Kyung Min LeeVA Salt Lake City Health Care System, Salt Lake City, UT, USA.
Myung-Shik LeeSoochunhyang Institute of Medi-bio Science and Division of Endocrinology, Department of Internal Medicine, Soochunhyang University College of Medicine, Cheonan, South Korea.
Nanette R LeeUSC-Office of Population Studies Foundation, University of San Carlos, Cebu City, Philippines.
Aaron LeongDepartment of Medicine, Harvard Medical School, Boston, MA, USA.
Liming LiDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
Yun LiDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Ruifang Li-GaoDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
Symen LigthartDepartment of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Cecilia M LindgrenWellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Allan LinnebergCenter for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.
Ching-Ti LiuDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Jianjun LiuGenome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.
Adam E LockeMcDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, USA.
Tin LouieDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
Jian'an LuanMRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Andrea O LukDepartment of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China.
Xi LuoDepartment of Biostatistics and Data Science, University of Texas Health Science Center at Houston School of Public Health, Houston, TX, USA.
Jun LvDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
Julie A LynchVA Salt Lake City Health Care System, Salt Lake City, UT, USA.
Valeriya LyssenkoDepartment of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.
Shiro MaedaLaboratory for Genomics of Diabetes and Metabolism, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Vasiliki MamakouDromokaiteio Psychiatric Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Sohail Rafik MansuriGenomic Research on Complex Diseases (GRC-Group), CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad, India.
Koichi MatsudaComputational Biology and Medical Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan.
Thomas MeitingerInstitute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Olle MelanderLund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden.
Andres MetspaluEstonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Huan MoCenter for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Andrew D MorrisUsher Institute to the Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
Filipe A MouraTIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Jerry L NadlerDepartment of Medicine and Pharmacology, New York Medical College, Valhalla, NY, USA.
Michael A NallsLaboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Uma NayakDepartment of Public Health Sciences and Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA.
Ioanna NtallaWilliam Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Yukinori OkadaDepartment of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
Lorena OrozcoInstituto Nacional de Medicina Genómica, Mexico City, Mexico.
Sanjay R PatelDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Snehal PatilDepartment of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
Pei PeiPeking University Center for Public Health and Epidemic Preparedness and Response, Beijing, China.
Mark A PereiraDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
Annette PetersInstitute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Fraser J PirieDepartment of Diabetes and Endocrinology, Nelson R. Mandela School of Medicine, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Hannah G PolikowskyDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Bianca PornealaDivision of General Internal Medicine, Massachusetts General Hospital, Boston, MA, USA.
Gauri PrasadAcademy of Scientific and Innovative Research, CSIR-Human Resource Development Campus, Ghaziabad, India.
Laura J Rasmussen-TorvikDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Alexander P ReinerFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Michael RodenGerman Center for Diabetes Research (DZD), Neuherberg, Germany.
Rebecca RohdeDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Katheryn RollInstitute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Charumathi SabanayagamSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Kevin SandowInstitute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Alagu SankareswaranGenomic Research on Complex Diseases (GRC-Group), CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad, India.
Naveed SattarSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Sebastian SchönherrInstitute of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria.
Mohammad ShahriarInstitute for Population and Precision Health (IPPH), Biological Sciences Division, University of Chicago, Chicago, IL, USA.
Botong ShenLaboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Jinxiu ShiShanghai-MOST Key Laboratory of Health and Disease Genomics, Shanghai Institute for Biomedical and Pharmaceutical Technologies, Shanghai, China.
Dong Mun ShinDivision of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, Korea.
Nobuhiro ShojimaDepartment of Diabetes and Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Jennifer A SmithDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Wing Yee SoDepartment of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China.
Alena StančákováInstitute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Valgerdur SteinthorsdottirdeCODE Genetics, Amgen, Reykjavik, Iceland.
Adrienne M StilpDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
Konstantin StrauchInstitute of Genetic Epidemiology, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, Neuherberg, Germany.
Kent D TaylorInstitute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Barbara ThorandInstitute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Unnur ThorsteinsdottirdeCODE Genetics, Amgen, Reykjavik, Iceland.
Brian TomlinsonDepartment of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China.
Tam C TranCenter for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Fuu-Jen TsaiDepartment of Medical Genetics and Medical Research, China Medical University Hospital, Taichung, Taiwan.
Jaakko TuomilehtoPopulation Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland.
Teresa Tusie-LunaUnidad de Biología Molecular y Medicina Genómica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Miriam S UdlerPrograms in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Adan Valladares-SalgadoUnidad de Investigacion Medica en Bioquimica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Rob M van DamSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Jan B van KlinkenEinthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Rohit VarmaSouthern California Eye Institute, CHA Hollywood Presbyterian Hospital, Los Angeles, CA, USA.
Niels Wacher-RodarteUnidad de Investigación Médica en Epidemiologia Clinica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Eleanor WheelerMRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Ananda R WickremasingheDepartment of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Ko Willems van DijkEinthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.
Daniel R WitteDepartment of Public Health, Aarhus University, Aarhus, Denmark.
Chittaranjan S YajnikDiabetology Research Centre, King Edward Memorial Hospital and Research Centre, Pune, India.
Ken YamamotoDepartment of Medical Biochemistry, Kurume University School of Medicine, Kurume, Japan.
Kenichi YamamotoDepartment of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
Kyungheon YoonDivision of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, Korea.
Canqing YuDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
Jian-Min YuanDivision of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA.
Salim YusufDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Matthew ZawistowskiDepartment of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
Liang ZhangSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Wei ZhengDivision of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
VA Million Veteran Program
Leslie J RaffelDepartment of Pediatrics, Division of Genetic and Genomic Medicine, UCI Irvine School of Medicine, Irvine, CA, USA.
Michiya IgaseDepartment of Anti-Aging Medicine, Ehime University Graduate School of Medicine, Touon, Japan.
Eli IppDepartment of Medicine, Division of Endocrinology and Metabolism, Lundquist Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.
Susan RedlineDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.
Yoon Shin ChoDepartment of Biomedical Science, Hallym University, Chuncheon, South Korea.
Lars LindDepartment of Medical Sciences, Uppsala University, Uppsala, Sweden.
Michael A ProvinceDivision of Statistical Genomics, Washington University School of Medicine, St Louis, MO, USA.
Myriam FornageInstitute of Molecular Medicine, University of Texas Health Science Center at Houston School of Public Health, Houston, TX, USA.
Craig L HanisHuman Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.
Erik IngelssonDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Alan B ZondermanLaboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Bruce M PsatyCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
Ya-Xing WangBeijing Institute of Ophthalmology, Ophthalmology and Visual Sciences Key Laboratory, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Charles N RotimiCenter for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Diane M BeckerDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Fumihiko MatsudaCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yongmei LiuDepartment of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Mitsuhiro YokotaKurume University School of Medicine, Kurume, Japan.
Sharon L R KardiaDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Patricia A PeyserDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
James S PankowDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
James C EngertDepartment of Medicine, McGill University, Montreal, Quebec, Canada.
Amélie BonnefondInserm U1283, CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, Lille University Hospital, Lille, France.
Philippe FroguelInserm U1283, CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, Lille University Hospital, Lille, France.
James G WilsonDivision of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Wayne H H SheuSchool of Medicine, National Defense Medical Center, Taipei, Taiwan.
Jer-Yuarn WuInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
M Geoffrey HayesDivision of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Ronald C W MaDepartment of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China.
Tien-Yin WongSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Dennis O Mook-KanamoriDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
Tiinamaija TuomiLund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden.
Giriraj R ChandakGenomic Research on Complex Diseases (GRC-Group), CSIR-Centre for Cellular and Molecular Biology (CSIR-CCMB), Hyderabad, India.
Francis S CollinsCenter for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Dwaipayan BharadwajSystems Genomics Laboratory, School of Biotechnology, Jawaharlal Nehru University, New Delhi, India.
Guillaume ParéPopulation Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada.
Michèle M SaleDepartment of Public Health Sciences and Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA.
Habibul AhsanInstitute for Population and Precision Health (IPPH), Biological Sciences Division, University of Chicago, Chicago, IL, USA.
Ayesha A MotalaDepartment of Diabetes and Endocrinology, Nelson R. Mandela School of Medicine, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Xiao-Ou ShuDivision of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Kyong-Soo ParkDepartment of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.
J Wouter JukemaDepartment of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
Miguel CruzUnidad de Investigacion Medica en Bioquimica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Yii-Der Ida ChenInstitute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
Stephen S RichCenter for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA.
Roberta McKean-CowdinDepartment of Population and Public Health Sciences, Keck School of Medicine of USC, Los Angeles, CA, USA.
Harald GrallertInstitute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Ching-Yu ChengSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Mohsen GhanbariDepartment of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
E-Shyong TaiSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Josee DupuisDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Norihiro KatoDepartment of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Markku LaaksoInstitute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Anna KöttgenInstitute of Genetic Epidemiology, Department of Data Driven Medicine, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.
Woon-Puay KohSingapore Institute for Clinical Sciences, Agency for Science Technology and Research (A*STAR), Singapore, Singapore.
Donald W BowdenCenter for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Colin N A PalmerPat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, University of Dundee, Dundee, UK.
Jaspal S KoonerDepartment of Cardiology, Ealing Hospital, London NorthWest Healthcare NHS Trust, London, UK.
Charles KooperbergFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Simin LiuDepartment of Epidemiology, Brown University School of Public Health, Providence, RI, USA.
Kari E NorthDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Danish SaleheenDepartment of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Torben HansenNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Oluf PedersenNovo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Nicholas J WarehamMRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Juyoung LeeDivision of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, Korea.
Bong-Jo KimDivision of Genome Science, Department of Precision Medicine, National Institute of Health, Cheongju-si, Korea.
Iona Y MillwoodNuffield Department of Population Health, University of Oxford, Oxford, UK.
Robin G WaltersNuffield Department of Population Health, University of Oxford, Oxford, UK.
Kari StefanssondeCODE Genetics, Amgen, Reykjavik, Iceland.
Emma AhlqvistLund University Diabetes Centre, Department of Clinical Sciences, Lund University, Skåne University Hospital, Malmö, Sweden.
Mark O GoodarziDepartment of Medicine, Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Karen L MohlkeDepartment of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Claudia LangenbergMRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, UK.
Christopher A HaimanDepartment of Preventive Medicine, Keck School of Medicine of USC, Los Angeles, CA, USA.
Ruth J F LoosCharles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jose C FlorezPrograms in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Daniel J RaderDepartment of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Marylyn D RitchieDepartment of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Sebastian ZöllnerDepartment of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.
Reedik MägiEstonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.
Nicholas A MarstonTIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Christian T RuffTIMI Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
David A van HeelBlizard Institute, Queen Mary University of London, London, UK.
Sarah FinerInstitute for Population Health Sciences, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Joshua C DennyCenter for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
Toshimasa YamauchiDepartment of Diabetes and Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Takashi KadowakiDepartment of Diabetes and Metabolic Diseases, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
John C ChambersDepartment of Epidemiology and Biostatistics, Imperial College London, London, UK.
Maggie C Y NgCenter for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Xueling SimSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Jennifer E BelowDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Philip S TsaoDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Kyong-Mi ChangCorporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.
Mark I McCarthyWellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-4393-0510
James B MeigsPrograms in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Anubha MahajanWellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-5585-3420
Cassandra N SpracklenDepartment of Biostatistics and Epidemiology, University of Massachusetts Amherst, Amherst, MA, USA.
Josep M MercaderPrograms in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-8494-3660
Michael BoehnkeDepartment of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-6442-7754
Jerome I RotterInstitute for Translational Genomics and Population Sciences, Department of Pediatrics, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.ORCID http://orcid.org/0000-0001-7191-1723
Marijana VujkovicCorporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0003-4924-5714
Benjamin F VoightCorporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA. bvoight28@gmail.com.ORCID http://orcid.org/0000-0002-6205-9994
Andrew P MorrisCentre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester, UK. andrew.morris-5@manchester.ac.uk.ORCID http://orcid.org/0000-0002-6805-6014
Eleftheria ZegginiInstitute of Translational Genomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany. eleftheria.zeggini@helmholtz-munich.de.ORCID http://orcid.org/0000-0003-4238-659X
National Institutes of Health · USUniversity of North Carolina at Chapel Hill · USHelmholtz Zentrum München · DEUCLA Medical Center · USBrigham and Women's Hospital · USQueen Mary University of London · GBUniversity of Copenhagen · DKBroad Institute · USUniversity of Michigan · USKorea National Institute of Health · KRNational University of Singapore · SGLeiden University Medical Center · NLUniversity of Cambridge · GBUniversity of Washington · USChinese University of Hong Kong · HKWake Forest University · USChicago Department of Public Health · USdeCODE Genetics (Iceland) · ISLund University · SENorthwestern University · US

Funding

Genetic analysis of type II diabetes in Finnish populationZIAHG000024 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI ERDOS, MICHAEL · 2009 to 2025
$38.2M
UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
MONITORING SOCIAL CHANGE: HEALTH, REPRODUCTION, AGINGR01HD030880 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ADAIR, LINDA S, POPKIN, BARRY M · 1994 to 2024
$27.0M
Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID P OLSON · 2013 to 2026
$24.3M
Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Kanakadurga Singer · 2010 to 2026
$20.3M
Targeted Genetic Analysis of T2D and Quantitative TraitsR01DK072193 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN L. MOHLKE · 2005 to 2026
$11.3M
Bridging the gap between type 2 diabetes GWAS and therapeutic targetsUM1DK126185 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CLAUSSNITZER, MELINA C, GLOYN, ANNA LOUISE · 2020 to 2024
$9.5M
CHARGE Consortium: Omics Discovery for CVD and Aging PhenotypesR01HL105756 · NHLBI · UNIVERSITY OF WASHINGTON · PI Bruce M Psaty, NICHOLAS L SMITH · 2011 to 2026
$9.5M
Functional Interrogation of T2D-associated genes in human stem cell-derived models and miceUM1DK126194 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI GRANT, STRUAN F A, KAESTNER, KLAUS H · 2020 to 2024
$8.8M
Genetic epidemiology of rare and regulatory variants for metabolic traitsR01DK093757 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN L. MOHLKE · 2011 to 2026
$8.2M
Identifying Genes for Type 2 Diabetes:FUSIONR01DK062370 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BOEHNKE, MICHAEL L, SCOTT, LAURA J. · 2003 to 2025
$6.7M
Hispanic Latino Lipid ConsortiumR01HL142302 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jennifer Below, JOSEPH MCCORMICK · 2018 to 2026
$5.8M
BLRD VA I01 BX003362Cancer Research UK 29186Medical Research Council MC_PC_14135Medical Research Council MC_U137686851Medical Research Council MC_UU_00017/1Medical Research Council MR/W029626/1NHGRI NIH HHS U01 HG011723NHLBI NIH HHS R01 HL142302NHLBI NIH HHS R01 HL153805NIA NIH HHS R00 AG066849NICHD NIH HHS R01 HD030880NIDDK NIH HHS K23 DK114551NIDDK NIH HHS L30 DK106874NIDDK NIH HHS L30 DK126146NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK089503NIDDK NIH HHS R01 DK062370NIDDK NIH HHS R01 DK072193NIDDK NIH HHS R01 DK078150NIDDK NIH HHS R01 DK093757NIDDK NIH HHS R01 DK118011NIDDK NIH HHS R01 DK134575NIDDK NIH HHS R01 DK139598NIDDK NIH HHS R03 DK131249NIDDK NIH HHS U01 DK105535NIDDK NIH HHS UM1 DK126185NIDDK NIH HHS UM1 DK126194NIEHS NIH HHS P30 ES010126Wellcome Trust 212946/Z/18/Z
6 · The paper itself

Abstract

Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes

Indexed as

Diabetes Mellitus, Type 2Disease ProgressionGenetic Predisposition to DiseaseGenome-Wide Association StudyAdipocytesChromatinCoronary Artery DiseaseDiabetic NephropathiesEndothelial CellsEnteroendocrine CellsEpigenomicsHumansIslets of LangerhansMultifactorial InheritancePeripheral Arterial DiseaseSingle-Cell AnalysisChromatin

Identifiers

PMID38374256
PMCPMC10937372
OpenAlexW4391925503

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